Job Description O01325 Confidence 100.00% Date Fri May 3 21:21:05 BST 2013 Rank 62 Aligned Residues 242 % Identity 29% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	W	Q	L	Y	H	E	Q	I	N	L	G	K	K	L	G	N	G	E	F	G	E	V	F	Q	G	V	L	S	V	G	I	F	T	N	D	V	E	V	A	V	K	T	M	K	G	S	K	V	T	A	D	E	R	I	T	F	L	R	E	A	N	L	M	L	K	L	N	H	K	Y	V	V	R	L	Y	G	V	A	T
Query Conservation
Alig confidence																															.	.	.	.																.	.	.	.	.	.	.	.
Template Conservation																															.	.	.	.																.	.	.	.	.	.	.	.
Template Sequence		E	Y	D	Y	E	Y	D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	D	L	.	.	.	.	S	N	Q	V	R	I	A	I	K	E	I	P	E	Q	P	.	.	.	.	.	.	.	.	L	H	E	E	I	A	L	H	K	H	L	K	H	K	N	I	V	Q	Y	L	G	S	F	S
Template Known Secondary structure							B		T	T	S	S	B							S	S	S								T	.	.	.	.	T	T														.	.	.	.	.	.	.	.									T	T				T	T	B
Template Predicted Secondary structure																															.	.	.	.																.	.	.	.	.	.	.	.
Template SS confidence
		672	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700					.	.	.	.	.	.	.	.	.	710	.	.	.	.	.									.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.
		267	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.			.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.
Predicted Secondary structure																														.	.																																					.
Query SS confidence																														.	.																																					.
Query Sequence		Q	Q	E	P	I	M	I	V	M	E	L	C	S	G	G	C	L	K	S	R	I	E	K	K	D	E	Q	L	.	.	S	D	V	L	K	R	K	Y	C	K	Q	I	A	K	G	M	R	Y	L	E	K	K	Q	V	I	H	R	D	L	A	A	R	N	V	L	L	.	D	K	S	D	N	C	K	I	S	D	F	G	L
Query Conservation																														.	.																																					.
Alig confidence																														.	.																																					.
Template Conservation
Template Sequence		E	N	G	F	I	K	I	F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K	Y	L	H	D	N	Q	I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G	T
Template Known Secondary structure			T	T										T	T		B								T	T				T	T																						T	T				S			S	G	G	G					T	T	T									S	S
Template Predicted Secondary structure
Template SS confidence
		746	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.
		344	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.			.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.		.	.	.	.	.	.	420
Predicted Secondary structure																															.	.																																										.
Query SS confidence																															.	.																																										.
Query Sequence		S	L	F	G	K	L	H	K	E	Q	K	L	M	K	V	P	I	R	W	L	A	P	E	T	L	L	K	G	I	.	.	Y	S	S	K	S	D	V	W	S	F	G	V	V	M	F	E	V	F	S	G	E	Y	P	Y	A	D	V	K	V	L	K	E	L	R	R	K	V	A	H	E	N	.	L	R	L	K	P	P	S
Query Conservation																															.	.																																										.
Alig confidence							.	.	.	.	.	.	.	.	.																.	.																																										.
Template Conservation							.	.	.	.	.	.	.	.	.
Template Sequence		S	K	R	L	T	.	.	.	.	.	.	.	.	.	G	T	L	Q	Y	M	A	P	E	I	I	D	K	G	P	R	G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H	P	E	I	P	E	S
Template Known Secondary structure							.	.	.	.	.	.	.	.	.			G	G	G										G	G	G		S																		S	S		T	T	G	G	G		S												T							T	T
Template Predicted Secondary structure							.	.	.	.	.	.	.	.	.
Template SS confidence
		826	.	.	.	830										.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.
		421	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	M	P	T	D	D	A	K	V	M	E	M	C	F	E	P	V	D	N	R	A	T	F	V	Q	V	C	N	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	S	A	E	A	K	A	F	I	L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	L	V	D
Template Known Secondary structure		S												T		S		T	T	T	S								T	S
Template Predicted Secondary structure
Template SS confidence
		907	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D