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Job DescriptionO01325
Confidence100.00%DateFri May 3 21:21:05 BST 2013
Rank216Aligned Residues233
% Identity28%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   188.190.........200.........210.........220.........230.........240.........250.........260.......
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Query Sequence  WQLYHEQINLGKKLGNGEFGEVFQGVLSVGIFTNDVEVAVKTMKGSKVTADERITFLREANLMLKLNHKYVVRLYGVATQ
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEK. . . . ATGRYYAMKILKKE. . . . . . . . . VIVANRVLQNSRHPFLTALKYSFQT
Template Known Secondary structure  T


TTSTTT....TT

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   112.......120.........130......... 140.........150... ......160.........170........
 
   268.270.........280.........290.........300.........310...... ...320.........330.........340......
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Query Sequence  QEPIMIVMELCSGGCLKSRIEKKDEQLSDVLKRKYCKQIAKGMRYLEKK. QVIHRDLAARNVLLDKSDNCKISDFGLSLF
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Template Sequence  HDRLCFVMEYANGGELFFHLSRERV. FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCK.
Template Known Secondary structure  SS

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   220.........230.........240.... .....250.........260.........270.........280.........290.......
 
   347..350.........360.........370.........380.........390.........400.........410.........420......
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Query Sequence  GKLHKEQKLMKVPIRWLAPETLLKGIYSSKSDVWSFGVVMFEVFSGEYPYADVKVLKELRRKVAHENLRLKPPSDMPTDD
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Template Sequence  . . . . . . . . . . . . EPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEE. . IRFPRTLGPEAK
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   298.300.........310.........320.........330.........340.........350. ........360...
 
   427..430.........440 .........
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Query Sequence  AKVMEMCFEPVDNR. . . . . ATFVQVCNR
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Template Sequence  SLLSGLLKKDPKQRLGGGSEDAKEIMQH
Template Known Secondary structure  T
SSTTTSTT
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   378.380.........390.........400.....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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