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Job DescriptionO01325
Confidence100.00%DateFri May 3 21:21:05 BST 2013
Rank208Aligned Residues250
% Identity23%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   193......200.........210.........220.........230.........240.........250.........260.... ....
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Query Sequence  EQINLGKKLGNGEFGEVFQGVLSVGIFTNDVEVAVKTMKGSKVTADERITFLREANLMLKLNHKYVVRLYGV. . . . ATQQ
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Template Sequence  RDITLLECVGKGRYGEVWRGSWQ. . . . . . GENVAVKIFSSRD. . . EKSWFRETELYNTVMLRHENILGFIASDMTSRHSS
Template Known Secondary structure  TTTTT......T
GGG...S



TTB

TT
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   206...210.........220........ .230.........240. ........250.........260.........270......
 
   269270.........280.........290.........300.........310........ .320.........330.........340
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Query Sequence  EPIMIVMELCSGGCLKSRIEKKDEQLSDVLKRKYCKQIAKGMRYLEKKQV. . . . . . . . IHRDLAARNVLLDKSDNCKISD
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Template Sequence  TQLWLITHYHEMGSLYDYLQLTT. . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIAD
Template Known Secondary structure 

TT
B

..B
S
B
STT
B

S

SGGG
TTS


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   277..280.........290......... 300.........310.........320.........330.........340.........350....
 
   341..... ...350.........360.........370.. .......380.........390.........400..
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Query Sequence  FGLSLF. . . . . GKLHKEQKLMKVPIRWLAPETLLKGI. . . . . . YSSKSDVWSFGVVMFEVFSGEYPYADVKVL. . . . . . .
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Template Sequence  LGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDV
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TT
TTTT








GGG

TT


TT
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BTTB





TTTTT
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   355....360.........370.........380.........390.........400.........410.........420.........430....
 
   403......410.........420 .........430.........440.........450...
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Query Sequence  . . . . . . . KELRRKVAHENLRLKPPS. . . . . . DMPTDDAKVMEMCFEPVDNRATFVQVCNRYKDL
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Template Sequence  VPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  S
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TTS






GGGGGS

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   435....440.........450.........460.........470.........480.........490........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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