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Job DescriptionO01325
Confidence100.00%DateFri May 3 21:21:05 BST 2013
Rank41Aligned Residues262
% Identity29%Templatec3lxkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   190.........200.........210.........220.........230.........240.........250.........260.......
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Query Sequence  LYHEQINLGKKLGNGEFGEVFQGVLSVGIFTNDVEVAVKTMKGSKVTADERITFLREANLMLKLNHKYVVRLYGVATQ. .
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Template Sequence  FEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHS. . GPDQQRDFQREIQILKALHSDFIVKYRGVSYGPG
Template Known Secondary structure 

GGGTT
TTSSS
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T


TTB

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   817..820.........830.........840.........850.........860 .........870.........880.........890....
 
   268.270.........280.........290.........300.........310.........320.........330.........340......
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Query Sequence  QEPIMIVMELCSGGCLKSRIEKKDEQLSDVLKRKYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSDNCKISDFGLSLF.
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Template Sequence  RQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLL
Template Known Secondary structure  S


TT
BGGG

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SGGGTT


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   895....900.........910.........920.........930.........940.........950.........960.........970....
 
   347..350.........360.........370.........380.........390........ .400.........410....
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Query Sequence  . . . GKLHKEQKLMKVPIRWLAPETLLKGIYSSKSDVWSFGVVMFEVFSGEYPYAD. . . . . . . . . VKVLKELRRKVAHENL
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Template Sequence  PLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMVPALSRLLELLEEGQR
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S

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S
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   975....980.........990.........1000.........1010.........1020.........1030.........1040.........1050....
 
   415....420.........430.........440.........450...
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Query Sequence  RLKPPSDMPTDDAKVMEMCFEPVDNRATFVQVCNRYKDL
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Template Sequence  LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML
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TT

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   1060.........1070.........1080.........1090........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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