Job Description O01325 Confidence 100.00% Date Fri May 3 21:21:05 BST 2013 Rank 244 Aligned Residues 253 % Identity 27% Template c3c1xA_ PDB info PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor Resolution 2.17 Å

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		186	.	.	.	190	.	.	.	.			.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.
Predicted Secondary structure											.	.
Query SS confidence											.	.
Query Sequence		E	E	W	Q	L	Y	H	E	Q	.	.	I	N	L	G	K	K	L	G	N	G	E	F	G	E	V	F	Q	G	V	L	S	V	G	I	F	T	N	D	V	E	V	A	V	K	T	M	K	G	S	K	V	T	A	D	E	R	I	T	F	L	R	E	A	N	L	M	L	K	L	N	H	K	Y	V	V	R	L	Y	G
Query Conservation											.	.
Alig confidence											.	.																									.																.
Template Conservation																																					.																.
Template Sequence		Q	H	V	V	I	G	P	S	S	L	I	V	H	F	N	E	V	I	G	R	G	H	F	G	C	V	Y	H	G	T	L	L	D	N	D	.	G	K	K	I	H	C	A	V	K	S	L	N	R	I	T	.	D	I	G	E	V	S	Q	F	L	T	E	G	I	I	M	K	D	F	S	H	P	N	V	L	S	L	L	G
Template Known Secondary structure		T	T	T	B			S	T	T													S	S	S										T	T	.	T												S		S	.		S											T	T	S	T	T				T	T	B
Template Predicted Secondary structure																																					.																.
Template SS confidence
		1067	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.		.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.		.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.
		264	.	.	.	.	.	270	.		.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.
Predicted Secondary structure										.
Query SS confidence										.
Query Sequence		V	A	T	Q	Q	E	P	I	.	M	I	V	M	E	L	C	S	G	G	C	L	K	S	R	I	E	K	K	D	E	Q	L	S	D	V	L	K	R	K	Y	C	K	Q	I	A	K	G	M	R	Y	L	E	K	K	Q	V	I	H	R	D	L	A	A	R	N	V	L	L	D	K	S	D	N	C	K	I	S	D	F	G
Query Conservation										.
Alig confidence										.
Template Conservation
Template Sequence		I	C	L	R	S	E	G	S	P	L	V	V	L	P	Y	M	K	H	G	D	L	R	N	F	I	R	N	E	T	H	N	P	T	V	K	D	L	I	G	F	G	L	Q	V	A	K	G	M	K	F	L	A	S	K	K	F	V	H	R	D	L	A	A	R	N	C	M	L	D	E	K	F	T	V	K	V	A	D	F	L
Template Known Secondary structure							S	S										T	T		B								T	T				B																					T	T				S				G	G	G					T	T
Template Predicted Secondary structure
Template SS confidence
		1145	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.
		343	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	S	L	F	G	K	L	H	K	E	Q	K	L	M	K	V	P	I	R	W	L	A	P	E	T	L	L	K	G	I	Y	S	S	K	S	D	V	W	S	F	G	V	V	M	F	E	V	F	S	G	E	Y	P	Y	A	D	V	K	V	L	K	E	L	R	R	K	V	A	H	E	N	L	R	L	K	P	P	S	D	M
Query Conservation
Alig confidence					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		P	V	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	W	M	A	L	E	S	L	Q	T	Q	K	F	T	T	K	S	D	V	W	S	F	G	V	L	L	W	E	L	M	T	R	G	A	P	P	Y	P	D	V	N	T	F	D	I	T	V	Y	L	L	Q	G	R	R	L	L	Q	P	E	Y	C	P
Template Known Secondary structure			G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	S																												T	T	S			S		T	T	S		S	S								T	T							T	T
Template Predicted Secondary structure					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1246	.	.																	.	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.
		423	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	T	D	D	A	K	V	M	E	M	C	F	E	P	V	D	N	R	A	T	F	V	Q	V	C	N	R	Y	K	D	L	T	S	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	P	L	Y	E	V	M	L	K	C	W	H	P	K	A	E	M	R	P	S	F	S	E	L	V	S	R	I	S	A	I	F	S	T
Template Known Secondary structure												T		S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D