Job Description O01325 Confidence 100.00% Date Fri May 3 21:21:05 BST 2013 Rank 307 Aligned Residues 247 % Identity 20% Template c2vx3D_ PDB info PDB header:transferase Chain: D: PDB Molecule:dual specificity tyrosine-phosphorylation- regulated PDBTitle: crystal structure of the human dual specificity tyrosine-2 phosphorylation-regulated kinase 1a Resolution 2.40 Å

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		193	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.							260	.	.	.	.	.	.
Predicted Secondary structure																																																																					.	.	.	.	.	.
Query SS confidence																																																																					.	.	.	.	.	.
Query Sequence		E	Q	I	N	L	G	K	K	L	G	N	G	E	F	G	E	V	F	Q	G	V	L	S	V	G	I	F	T	N	D	V	E	V	A	V	K	T	M	K	G	S	K	V	T	A	D	E	R	I	T	F	L	R	E	A	N	L	M	L	K	L	N	H	K	Y	V	V	.	.	.	.	.	.	R	L	Y	G	V	A	T
Query Conservation																																																																					.	.	.	.	.	.
Alig confidence																									.	.	.	.													.	.	.																										.	.	.	.	.	.
Template Conservation																									.	.	.	.													.	.	.
Template Sequence		D	R	Y	E	I	D	S	L	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	R	.	.	.	.	V	E	Q	E	W	V	A	I	K	I	I	K	.	.	.	N	K	K	A	F	L	N	Q	A	Q	I	E	V	R	L	L	E	L	M	N	K	H	D	T	E	M	K	Y	Y	I	V	H	L	K	R	H	F	M
Template Known Secondary structure		T	T											T	T									T	.	.	.	.	T	T	T										.	.	.	S	S																				S	S	S	S	G	G	G	G	B
Template Predicted Secondary structure																									.	.	.	.													.	.	.
Template SS confidence
		157	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.					180	.	.	.	.	.	.	.	.	.	190	.				.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.
		267	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.					.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.
Predicted Secondary structure																																																					.	.	.	.
Query SS confidence																																																					.	.	.	.
Query Sequence		Q	Q	E	P	I	M	I	V	M	E	L	C	S	G	G	C	L	K	S	R	I	E	K	K	D	E	Q	L	S	D	V	L	K	R	K	Y	C	K	Q	I	A	K	G	M	R	Y	L	E	K	K	Q	.	.	.	.	V	I	H	R	D	L	A	A	R	N	V	L	L	D	K	S	D	N	C	K	I	S	D	F	G
Query Conservation																																																					.	.	.	.
Alig confidence																																																					.	.	.	.
Template Conservation
Template Sequence		F	R	N	H	L	C	L	V	F	E	M	L	S	Y	N	L	Y	D	L	L	R	N	T	N	F	R	G	V	S	L	N	L	T	R	K	F	A	Q	Q	M	C	T	A	L	L	F	L	A	T	P	E	L	S	I	I	H	C	D	L	K	P	E	N	I	L	L	C	N	P	K	R	S	A	I	K	I	V	D	F	G
Template Known Secondary structure			T	T												B								T	T	T																								S	T	T	T					S				G	G	G				S	S	T	T	S									T
Template Predicted Secondary structure
Template SS confidence
		230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.
		343	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.
Predicted Secondary structure																																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		L	S	L	F	G	K	L	H	K	E	Q	K	L	M	K	V	P	I	R	W	L	A	P	E	T	L	L	K	G	I	Y	S	S	K	S	D	V	W	S	F	G	V	V	M	F	E	V	F	S	G	E	Y	P	Y	A	D	V	K	V	L	K	E	L	R	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence														.	.	.																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation														.	.	.
Template Sequence		S	S	C	Q	L	G	Q	R	I	Y	Q	I	.	.	.	Q	S	R	F	Y	R	S	P	E	V	L	L	G	M	P	Y	D	L	A	I	D	M	W	S	L	G	C	I	L	V	E	M	H	T	G	E	P	L	F	S	G	A	N	E	V	D	Q	M	N	K	I	V	E	V	L	G	I	P	P	A	H	I	L	D	Q
Template Known Secondary structure		T				T	T							.	.	.			G	G	G							T	T					T																	S	S		S	S			S	S														S							T	T
Template Predicted Secondary structure														.	.	.
Template SS confidence
		310	.	.	.	.	.	.	.	.	.	320	.				.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
																																														408	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	V	A	H	E	N	L	R	L	K	P	P	S	D	M	P	T	D	D	A	K	V	M	E	M	C	F	E	P	V	D	N	R	A	T	F
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	P	K	A	R	K	F	F	E	K	L	P	D	G	T	W	N	L	K	K	T	K	R	E	Y	K	P	P	G	T	R	K	L	H	N	I	L	G	V	E	T	G	G	P	G	G	R	R	A	G	E	S	G	H	T	V	A	D	Y	L	K	F	K	D	L	I	L	R	M	L	D	Y	D	P	K	T	R	I	Q	P
Template Known Secondary structure			T	T	G	G	G	T					T	T	S											S			T	T		S						T	T	T	T	T	T	S	G	G	G	T	T	T	T		T	T																	T		S		T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		388	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.
		444	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	Q	V	C	N	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	Y	A	L	Q	H
Template Known Secondary structure						T	S
Template Predicted Secondary structure
Template SS confidence
		471	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D