Job Description O01325 Confidence 100.00% Date Fri May 3 21:21:05 BST 2013 Rank 277 Aligned Residues 244 % Identity 22% Template c2pvmA_ PDB info PDB header:transferase Chain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2 Resolution 2.00 Å

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		193	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270
Predicted Secondary structure																																																																																.	.
Query SS confidence																																																																																.	.
Query Sequence		E	Q	I	N	L	G	K	K	L	G	N	G	E	F	G	E	V	F	Q	G	V	L	S	V	G	I	F	T	N	D	V	E	V	A	V	K	T	M	K	G	S	K	V	T	A	D	E	R	I	T	F	L	R	E	A	N	L	M	L	K	L	N	H	K	Y	V	V	R	L	Y	G	V	A	T	Q	Q	E	P	.	.
Query Conservation																																																																																.	.
Alig confidence																									.	.	.	.																.	.	.	.	.																																.	.
Template Conservation																									.	.	.	.																.	.	.	.	.
Template Sequence		D	D	Y	E	V	V	R	K	V	G	R	G	K	Y	S	E	V	F	E	G	I	N	V	.	.	.	.	N	N	N	E	K	C	I	I	K	I	L	K	P	V	K	.	.	.	.	.	K	K	K	I	K	R	E	I	K	I	L	Q	N	L	G	G	P	N	I	V	K	L	L	D	I	V	R	D	Q	H	S	K	T
Template Known Secondary structure		G	G											S	S									T	.	.	.	.	T	T											S			.	.	.	.	.																	T	T	B										T	T	T
Template Predicted Secondary structure																									.	.	.	.																.	.	.	.	.
Template SS confidence
		37	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.					60	.	.	.	.	.	.	.	.	.	70	.	.	.	.						.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.
		271	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.		.	.	.	.	340	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																			.
Query SS confidence																																																																			.
Query Sequence		I	M	I	V	M	E	L	C	S	G	G	C	L	K	S	R	I	E	K	K	D	E	Q	L	S	D	V	L	K	R	K	Y	C	K	Q	I	A	K	G	M	R	Y	L	E	K	K	Q	V	I	H	R	D	L	A	A	R	N	V	L	L	D	K	S	D	N	.	C	K	I	S	D	F	G	L	S	L	F	G	K	L
Query Conservation																																																																			.
Alig confidence																				.	.	.	.																																												.
Template Conservation																				.	.	.	.
Template Sequence		P	S	L	I	F	E	Y	V	N	N	T	D	F	K	V	L	Y	P	.	.	.	.	T	L	T	D	Y	D	I	R	Y	Y	I	Y	E	L	L	K	A	L	D	Y	C	H	S	Q	G	I	M	H	R	D	V	K	P	H	N	V	M	I	D	H	E	L	R	K	L	R	L	I	D	W	G	L	A	E	F	Y	H	P
Template Known Secondary structure																		G	G	.	.	.	.	G																							T	T							S	G	G	G					T	T	T	T								T	T						T
Template Predicted Secondary structure																				.	.	.	.
Template SS confidence
		109	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.					.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.
		350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370		.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.
Predicted Secondary structure																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		H	K	E	Q	K	L	M	K	V	P	I	R	W	L	A	P	E	T	L	L	K	.	G	I	Y	S	S	K	S	D	V	W	S	F	G	V	V	M	F	E	V	F	S	G	E	Y	P	Y	A	D	V	K	V	L	K	E	L	R	R	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		G	K	E	Y	N	V	R	V	A	S	R	Y	F	K	G	P	E	L	L	V	D	L	Q	D	Y	D	Y	S	L	D	M	W	S	L	G	C	M	F	A	G	M	I	F	R	K	E	P	F	F	Y	G	H	D	N	H	D	Q	L	V	K	I	A	K	V	L	G	T	D	G	L	N	A	Y	L	N	K	Y	R	I	E
Template Known Secondary structure		T					S			S		G	G	G							T	T			S			T																	T		S	S	S	S			S	S																								T	T
Template Predicted Secondary structure
Template SS confidence
		185	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.
																		409	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	A	H	E	N	L	R	L	K	P	P	S	D	M	P	T	D	D	A	K	V	M	E	M	C	F	E	P	V	D	N	R	A	T	F	V	Q	V	C	N	R
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		L	D	P	Q	L	E	A	L	V	G	R	H	S	R	K	P	W	L	K	F	M	N	A	D	N	Q	H	L	V	S	P	E	A	I	D	F	L	D	K	L	L	R	Y	D	H	Q	E	R	L	T	A	L	E	A	M	T	H
Template Known Secondary structure																		G	G	G	G			T	T	T	G	G	G											T	T			S	S	T	T	T	S									S
Template Predicted Secondary structure
Template SS confidence
		265	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D