|   |   |
193 | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | Q | I | N | L | G | K | K | L | G | N | G | E | F | G | E | V | F | Q | G | V | L | S | V | G | I | F | T | N | D | V | E | V | A | V | K | T | M | K | G | S | K | V | T | A | D | E | R | I | T | F | L | . |
. |
. |
. |
. |
. |
. |
. |
R | E | A | N | L | M | L | K | L | N | H | K | Y | V | V | R | L | Y | G | V |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|   |   |   |
|
|   |
|   |   |
|   |
|
|   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
| Template Sequence |   |
R | Q | W | K | L | K | S | F | Q | T | R | D | N | Q | G | I | L | Y | E | A | A | P | . |
. |
. |
. |
. |
. |
. |
T | S | K | F | S | L | K | L | D | A | K | D | G | R | L | F | N | E | Q | N | F | F | Q | R | A | A | K | P | L | Q | V | N | K | W | K | K | L | Y | S | T | P | L | L | A | I | P | T | C | M | G | F |
| Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  | T | T | S | T |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |
| S |
|
|
|
|
|  |  |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
|   |
|   |   |
265 | . | . | . | . | 270 | |
. | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | |
. | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | |
|
. | . | 340 |
| Predicted Secondary structure |   |
 |  |  |
|
|  | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
| . | . |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
| Query Sequence |   |
A | T | Q | Q | E | P | . |
I | M | I | V | M | E | L | C | S | G | G | C | L | K | S | R | I | E | K | K | D | E | Q | . |
L | S | D | V | L | K | R | K | Y | C | K | Q | I | A | K | G | M | R | Y | L | E | K | K | Q | V | I | H | R | D | L | A | A | R | N | V | L | L | D | K | S | D | N | C | K | . |
. |
I | S | D |
| Query Conservation |   |
  |   |   |   |   |   | . |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   | . |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|   |
|
|   |   |   |
|
|
|
|   |   |   |   |   |   |
| . | . |
|   |
|
| Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |
|   |   | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|
| Template Sequence |   |
G | V | H | Q | D | K | Y | R | F | L | V | L | P | S | L | . |
G | R | S | L | Q | S | A | L | D | V | S | P | K | H | V | L | S | E | R | S | V | L | Q | V | A | C | R | L | L | D | A | L | E | F | L | H | E | N | E | Y | V | H | G | N | V | T | A | E | N | I | F | V | D | P | E | D | Q | S | Q | V | T | L | A | G |
| Template Known Secondary structure |   |
 |  |  | T | T | T |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  | S | G | G | G |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
| S |
|
|
| G | G | G |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
|
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
|   |
|   |   |
341 | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
F | G | L | S | L | F | G | K | L | H | K | E | Q | K | L | M | . |
. |
. |
. |
. |
. |
. |
. |
K | V | P | I | R | W | L | A | P | E | T | L | L | K | G | I | Y | S | S | K | S | D | V | W | S | F | G | V | V | M | F | E | V | F | S | G | E | Y | P | Y | A | D | V | K | V | L | K | E | L | R | R | K | V | A | H | E |
| Query Conservation |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Y | G | F | A | F | R | Y | C | P | S | G | K | H | V | A | Y | V | E | G | S | R | S | P | H | E | G | D | L | E | F | I | S | M | D | L | H | K | G | C | G | P | S | R | R | S | D | L | Q | S | L | G | Y | C | M | L | K | W | L | Y | G | F | L | P | W | T | N | C | L | P | N | T | E | D | I | M | K | Q | K | Q | K |
| Template Known Secondary structure |   |
G | G | G |
| B |
| S | S | G | G | G |
|
|
|
|
|
| T | T | S | S |
| T | T |
| S |
| T | T | T |
|
|  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| T | T | G | G | G | T | T |
|  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
327 | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . |
|   |
|   |   |
413 | . | . | . | . | . | . | 420 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
N | L | R | L | K | P | P | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
D | M | P | T | D | D | A | K | V | M | E | M | C | F | E | P | V | D | N | R | A | T | F | V | Q | V | C | N | R | Y | K | D | L |
| Query Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |
| Template Sequence |   |
F | V | D | K | P | G | P | F | V | G | P | C | G | H | W | I | R | P | S | E | T | L | Q | K | Y | L | K | V | V | M | A | L | T | Y | E | E | K | P | P | Y | A | M | L | R | N | N | L | E | A | L |
| Template Known Secondary structure |   |
 |  |  | S |
|
|
|  |  |
| T | T | S |
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
407 | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . |
|   |