Job Description O01325 Confidence 100.00% Date Fri May 3 21:21:05 BST 2013 Rank 6 Aligned Residues 412 % Identity 27% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:63.074 Y:73.931 Z:48.371

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		26	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	L	L	K	A	T	D	E	T	S	S	D	G	A	S	T	S	L	S	K	S	V	E	E	S	A	P	N	K	D	K	S	N	S	S	L	V	K	S	H	H	V	L	K	I	K	L	K	K	I	T	N	W	S	G	C	S	G	A	L	L	D	D	E	P	F	Y	H	G	Y	M	S	R	E	E	S	E	K	L	V
Query Conservation
Alig confidence																																	.																											.	.
Template Conservation																																	.																											.	.
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	S	G	.	E	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	S	.	.	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T										T	.	T							T	T	T								G	G	G				T	T	S	.	.	G	G	G	S	T	T			T	T
Template Predicted Secondary structure																																	.																											.	.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.		.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.			.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.
		106	.					.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130				.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150		.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.
Predicted Secondary structure				.	.	.	.																								.	.	.																					.																							.	.	.	.	.
Query SS confidence				.	.	.	.																								.	.	.																					.																							.	.	.	.	.
Query Sequence		R	S	.	.	.	.	Q	G	E	F	L	L	R	K	T	E	L	T	K	R	G	E	V	V	V	L	S	V	F	.	.	.	W	D	E	G	V	H	H	L	V	V	E	K	A	N	N	G	L	Y	Y	L	.	K	E	F	C	F	E	N	I	S	D	L	V	R	Y	H	H	Q	T	R	A	S	V	.	.	.	.	.
Query Conservation				.	.	.	.																								.	.	.																					.																							.	.	.	.	.
Alig confidence				.	.	.	.																								.	.	.																					.																							.	.	.	.	.
Template Conservation
Template Sequence		L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y	K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S
Template Known Secondary structure		T	S	T	T			T	T								S	S	S	T	T											T	T	T										B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S
Template Predicted Secondary structure
Template SS confidence
		138	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.
			173	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.
Predicted Secondary structure		.
Query SS confidence		.
Query Sequence		.	Y	K	S	G	I	K	L	F	S	W	V	V	R	E	E	W	Q	L	Y	H	E	Q	I	N	L	G	K	K	L	G	N	G	E	F	G	E	V	F	Q	G	V	L	S	V	G	I	F	T	N	D	V	E	V	A	V	K	T	M	K	G	S	K	V	T	A	D	E	R	I	T	F	L	R	E	A	N	L	M	L
Query Conservation		.
Alig confidence		.																																												.	.	.	.	.																				.	.	.
Template Conservation																																														.	.	.	.	.																				.	.	.
Template Sequence		V	P	C	M	S	S	K	P	Q	K	P	W	E	K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	.	.	.	.	.	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	.	.	.	F	L	A	E	A	N	V	M	K
Template Known Secondary structure		S	B												T	T		S	B			G	G	G											T	T									T	.	.	.	.	.	T	T												S	S					.	.	.
Template Predicted Secondary structure																																														.	.	.	.	.																				.	.	.
Template SS confidence
		218	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.						.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280				.	.	.	.	.	.	.	.	.
		252	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.		.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330
Predicted Secondary structure																																												.
Query SS confidence																																												.
Query Sequence		K	L	N	H	K	Y	V	V	R	L	Y	G	V	A	T	Q	Q	E	P	I	M	I	V	M	E	L	C	S	G	G	C	L	K	S	R	I	E	K	K	D	E	Q	.	L	S	D	V	L	K	R	K	Y	C	K	Q	I	A	K	G	M	R	Y	L	E	K	K	Q	V	I	H	R	D	L	A	A	R	N	V	L	L
Query Conservation																																												.
Alig confidence																.																												.
Template Conservation																.
Template Sequence		T	L	Q	H	D	K	L	V	K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V
Template Known Secondary structure		T				T	T	B								.		S	S	S									T	T		B							S	T	T	G	G	G																							T	T				S			S	G	G	G
Template Predicted Secondary structure																.
Template SS confidence
		290	.	.	.	.	.	.	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
		331	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.		.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																															.
Query SS confidence																																																															.
Query Sequence		D	K	S	D	N	C	K	I	S	D	F	G	L	S	L	F	G	K	L	H	K	E	Q	K	L	M	K	V	P	I	R	W	L	A	P	E	T	L	L	K	G	I	Y	S	S	K	S	D	V	W	S	F	G	V	V	M	F	E	V	F	S	.	G	E	Y	P	Y	A	D	V	K	V	L	K	E	L	R	R	K	V
Query Conservation																																																															.
Alig confidence																		.	.	.	.	.	.	.	.	.	.	.																																			.										.
Template Conservation																		.	.	.	.	.	.	.	.	.	.	.																																													.
Template Sequence		S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	V	.	.	.	.	.	.	.	.	.	.	.	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	.	N	P	E	V	I	R	A	L
Template Known Secondary structure			T	T								T	T	G	G	G	T	.	.	.	.	.	.	.	.	.	.	.			G	G	G	S																												T	T	T			S	S	T	T			.
Template Predicted Secondary structure																		.	.	.	.	.	.	.	.	.	.	.																																													.
Template SS confidence
		369	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.												.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.		.	430	.	.	.	.	.	.
		410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	H	E	N	L	R	L	K	P	P	S	D	M	P	T	D	D	A	K	V	M	E	M	C	F	E	P	V	D	N	R	A	T	F	V	Q	V	C	N	R	Y	K	D	L	T	S	P	L	P	T	W	N
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S	Q	E
Template Known Secondary structure			T	T							T	T													T		S	S	G	G	G	S												T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.