Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 72 Aligned Residues 266 % Identity 27% Template c4e1zA_ PDB info PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor Resolution 2.50 Å

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		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.				.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.
Predicted Secondary structure																																			.	.	.
Query SS confidence																																			.	.	.
Query Sequence		S	P	W	L	I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	.	.	.	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I
Query Conservation																																			.	.	.
Alig confidence																																			.	.	.
Template Conservation
Template Sequence		D	P	T	V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	E	G	C	G	P	Q	L	R	S	G	W	Q	R	E	I	E	I	L	R	T	L	Y	H	E	H	I	V	K	Y	K	G	C	C	E
Template Known Secondary structure			T	T	B			G	G	G											S	S										T	T			S	S											T	T																						T	T	B
Template Predicted Secondary structure
Template SS confidence
		884	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.
		199	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	E	H	P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	K	K	N	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	N	K	D
Query Conservation
Alig confidence																.
Template Conservation																.
Template Sequence		D	K	S	V	Q	L	V	M	E	Y	V	P	L	G	.	S	L	R	D	Y	L	P	R	H	C	V	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	A	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A	V	P
Template Known Secondary structure													T	T		.						G	G	G	S																								T	T				S			S	G	G	G					G	G	G								T	T
Template Predicted Secondary structure																.
Template SS confidence
		964	.	.	.	.	.	970	.	.	.	.	.	.	.		.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.
		279					280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.															330	.	.	.	.	.	.	.	.	.	340
Predicted Secondary structure			.	.	.	.																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence			.	.	.	.																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	.	.	.	.	I	K	D	E	T	L	E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	T	K	I	Q	T	R	A	K	I	V
Query Conservation			.	.	.	.																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence			.	.	.	.																																											.								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																	.
Template Sequence		E	G	H	E	Y	Y	R	V	R	E	D	G	D	S	P	V	F	W	Y	A	P	E	C	L	K	E	C	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	Y	C	D	S	N	Q	S	P	H	T	K	F	T	E	L	I	G	H	T	Q	G	Q	M	T	V	L	R	L	T	E	L	L
Template Known Secondary structure		T	T		S								S	S	S		G	G	G								S																					T	.	T	T		T	T	S	S											S
Template Predicted Secondary structure																																																	.
Template SS confidence
		1046	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.
		341	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390
Predicted Secondary structure
Query SS confidence
Query Sequence		V	N	D	Y	R	M	K	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L	R	E	F	Y	E	S	K	K
Query Conservation
Alig confidence																						.
Template Conservation																						.
Template Sequence		E	R	G	E	R	L	P	R	P	D	R	C	P	C	E	I	Y	H	L	M	.	K	N	C	W	E	T	E	A	S	F	R	P	T	F	Q	N	L	V	P	I	L	Q	T	A	Q	E	K	Y	Q
Template Known Secondary structure				T							T	T										.				T		S	S	G	G	G	S
Template Predicted Secondary structure																						.
Template SS confidence
		1125	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.		.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D