Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 220 Aligned Residues 254 % Identity 24% Template c3zonA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: human tyk2 pseudokinase domain bound to a kinase inhibitor Resolution 2.15 Å

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		119	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	E	R	S	P	W	L	I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I
Query Conservation
Alig confidence																																			.	.														.
Template Conservation																																			.	.														.
Template Sequence		S	Q	L	S	F	H	R	V	D	Q	K	E	I	T	Q	L	S	H	L	G	Q	G	T	R	T	N	V	Y	E	G	R	L	R	.	.	V	E	L	R	V	V	L	K	V	L	D	P	S	.	H	H	D	I	A	L	A	F	Y	E	T	A	S	L	M	S	Q	V	S	H	T	H	L	A	F	V	H	G	V	C	V
Template Known Secondary structure											G	G	G											T	T										.	.												S		.																T	T				T	T	B
Template Predicted Secondary structure																																			.	.														.
Template SS confidence
		577	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.			610	.	.	.	.	.	.	.	.	.	620	.	.		.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.
		199	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.			220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
Predicted Secondary structure																							.	.
Query SS confidence																							.	.
Query Sequence		H	E	H	P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	.	.	K	K	N	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	N
Query Conservation																							.	.
Alig confidence																							.	.
Template Conservation
Template Sequence		R	G	P	E	N	I	M	V	T	E	Y	V	E	H	G	P	L	D	V	W	L	R	R	E	R	G	H	V	P	M	A	W	K	M	V	V	A	Q	Q	L	A	S	A	L	S	Y	L	E	N	K	N	L	V	H	G	N	V	C	G	R	N	I	L	L	A	R	L	G	L	A	E	G	T	S	P	F	I	K	L	S
Template Known Secondary structure			T	T										T	T		B								T	T	T																								T	T							S	G	G	G									S	T	T
Template Predicted Secondary structure
Template SS confidence
		679	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.
		277	.	.	280	.	.	.	.	.	.					.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.
Predicted Secondary structure												.	.	.	.
Query SS confidence												.	.	.	.
Query Sequence		K	D	E	I	K	D	E	T	L	E	.	.	.	.	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	T	K	I	Q	T	R	A	K	I	V	V	N	D	Y	R	M	K	M	P	D	G	T
Query Conservation												.	.	.	.
Alig confidence												.	.	.	.													.	.	.																																														.	.	.	.	.	.
Template Conservation																												.	.	.																																														.	.	.	.	.	.
Template Sequence		D	P	G	V	G	L	G	A	L	S	R	E	E	R	V	E	R	I	P	W	L	A	P	E	C	L	.	.	.	P	L	S	T	A	M	D	K	W	G	F	G	A	T	L	L	E	I	C	F	D	G	E	A	P	L	Q	S	R	S	P	S	E	K	E	H	F	Y	Q	R	Q	H	R	L	P	.	.	.	.	.	.
Template Known Secondary structure					S		G	G	G	S								T	T	T	T	S		G	G	G		.	.	.				T	T															T	T	T			T	T	T	T	S											T	T					.	.	.	.	.	.
Template Predicted Secondary structure																												.	.	.																																														.	.	.	.	.	.
Template SS confidence
		759	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.				.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.
		353	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L	R	E	F
Query Conservation
Alig confidence										.
Template Conservation										.
Template Sequence		E	P	Q	L	A	T	L	T	.	S	Q	C	L	T	Y	E	P	T	Q	R	P	S	F	R	T	I	L	R	D	L	T	R	L
Template Known Secondary structure										.				T		S	S	G	G	G	S												T	T
Template Predicted Secondary structure										.
Template SS confidence
		835	.	.	.	.	840	.	.		.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D