Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 75 Aligned Residues 239 % Identity 26% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		123	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	W	L	I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I	H	E	H	P
Query Conservation
Alig confidence																													.																	.	.	.	.	.	.	.
Template Conservation																													.																	.	.	.	.	.	.	.
Template Sequence		E	Y	D	Y	E	Y	D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	.	D	L	S	N	Q	V	R	I	A	I	K	E	I	P	E	Q	.	.	.	.	.	.	.	P	L	H	E	E	I	A	L	H	K	H	L	K	H	K	N	I	V	Q	Y	L	G	S	F	S	E	N	G	F
Template Known Secondary structure							B		T	T	S	S	B							S	S	S							.		T	T	T													.	.	.	.	.	.	.										T	T				T	T	B										T	T
Template Predicted Secondary structure																													.																	.	.	.	.	.	.	.
Template SS confidence
		672	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.		.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.								.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.
		203	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.					.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260		.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.
Predicted Secondary structure																						.	.	.	.																																							.
Query SS confidence																						.	.	.	.																																							.
Query Sequence		L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	K	K	N	.	.	.	.	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	.	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	N	K
Query Conservation																						.	.	.	.																																							.
Alig confidence																						.	.	.	.																																							.
Template Conservation
Template Sequence		I	K	I	F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K	Y	L	H	D	N	Q	I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G	T	S	K	R	L
Template Known Secondary structure										T	T		B								T	T				T	T																						T	T				S			S	G	G	G					T	T	T									S	S
Template Predicted Secondary structure
Template SS confidence
		750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.
		278	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.			.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.
Predicted Secondary structure																											.	.																													.
Query SS confidence																											.	.																													.
Query Sequence		D	E	I	K	D	E	T	L	E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	.	.	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	.	T	K	I	Q	T	R	A	K	I	V	V	N	D	Y	R	M	K	M	P	D	G	T	H	P
Query Conservation																											.	.																													.
Alig confidence			.	.	.	.	.	.	.	.	.																.	.																				.									.
Template Conservation			.	.	.	.	.	.	.	.	.																																					.
Template Sequence		T	.	.	.	.	.	.	.	.	.	G	T	L	Q	Y	M	A	P	E	I	I	D	K	G	P	R	G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	.	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H	P	E	I	P	E	S	M	S	A
Template Known Secondary structure			.	.	.	.	.	.	.	.	.			G	G	G										G	G	G		S																		.	S	S		T	T	G	G	G		S												T							T	T	S
Template Predicted Secondary structure			.	.	.	.	.	.	.	.	.																																					.
Template SS confidence
		840										.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.		.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.
		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
Predicted Secondary structure
Query SS confidence
Query Sequence		T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K
Query Conservation
Alig confidence								.
Template Conservation								.
Template Sequence		E	A	K	A	F	I	.	L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	L	V
Template Known Secondary structure								.				T		S		T	T	T	S								T
Template Predicted Secondary structure								.
Template SS confidence
		910	.	.	.	.	.		.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D