Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 194 Aligned Residues 251 % Identity 24% Template c3mtfB_ PDB info PDB header:transferase Chain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor Resolution 2.15 Å

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		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.					.	.	.	200	.	.	.
Predicted Secondary structure																																																																							.	.	.	.
Query SS confidence																																																																							.	.	.	.
Query Sequence		H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	.	.	.	.	A	I	H	E	H	P	L
Query Conservation																																																																							.	.	.	.
Alig confidence																									.	.	.																				.	.																							.	.	.	.
Template Conservation																									.	.	.																				.	.
Template Sequence		A	R	D	I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G	S	W	.	.	.	Q	G	E	N	V	A	V	K	I	F	S	S	R	D	E	K	S	W	F	.	.	R	E	T	E	L	Y	N	T	V	M	L	R	H	E	N	I	L	G	F	I	A	S	D	M	T	S	R	H	S	S	T	Q	L
Template Known Secondary structure		T	T	T											T	T									.	.	.	T	T										G	G	G						.	.									S					T	T	B												T	T
Template Predicted Secondary structure																									.	.	.																				.	.
Template SS confidence
		205	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.				.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.			.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.
		204	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.									.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.
Predicted Secondary structure																																															.	.	.	.	.	.	.	.
Query SS confidence																																															.	.	.	.	.	.	.	.
Query Sequence		M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	K	K	N	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	.	.	.	.	.	.	.	.	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D
Query Conservation																																															.	.	.	.	.	.	.	.
Alig confidence																																															.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		W	L	I	T	H	Y	H	E	M	G	S	L	Y	D	Y	L	Q	L	T	T	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G	L	A	H	L	H	I	E	I	F	G	T	Q	G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V	K	K	N	G	Q	C	C	I	A	D	L	G	L	A	V
Template Known Secondary structure									T	T		B										B																					S		B		S	T	T		B						S			S	G	G	G					T	T	S								T	T
Template Predicted Secondary structure
Template SS confidence
		280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
		276						.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.							.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.
Predicted Secondary structure			.	.	.	.	.																											.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence			.	.	.	.	.																											.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		N	.	.	.	.	.	K	D	E	I	K	D	E	T	L	E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	.	.	.	.	.	.	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	T	K	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation			.	.	.	.	.																											.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence			.	.	.	.	.																											.	.	.	.	.	.																				.											.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																											.
Template Sequence		M	H	S	Q	S	T	N	Q	L	D	V	G	N	N	P	R	V	G	T	K	R	Y	M	A	P	E	V	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E	V	A	R	.	R	M	V	S	N	G	I	V	E	D	Y	K	P	P	F	Y	D	V	V	P	N	D
Template Known Secondary structure					T	T	T	T													G	G	G							T	T				T	T																						T	.	T	B		B	T	T	B							T	T	T	T	T	S		S	S
Template Predicted Secondary structure																																																											.
Template SS confidence
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.		.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.
					333	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.						.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Predicted Secondary structure		.	.	.																				.	.	.	.	.
Query SS confidence		.	.	.																				.	.	.	.	.
Query Sequence		.	.	.	I	Q	T	R	A	K	I	V	V	N	D	Y	R	M	K	M	P	D	G	.	.	.	.	.	T	H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L	R	E	F
Query Conservation		.	.	.																				.	.	.	.	.
Alig confidence		.	.	.																				.	.	.	.	.										.
Template Conservation																																						.
Template Sequence		P	S	F	E	D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K	L	M	.	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K	T	L	T	K	I
Template Known Secondary structure												T	T	S								G	G	G	G	G	S											.						S	S	G	G	G	S
Template Predicted Secondary structure																																						.
Template SS confidence
		439	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.		.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D