Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 54 Aligned Residues 257 % Identity 26% Template c3lxkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.00 Å

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		126	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.				.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.			200
Predicted Secondary structure																												.	.	.																																																	.	.
Query SS confidence																												.	.	.																																																	.	.
Query Sequence		I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	.	.	.	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I	H	.	.	E
Query Conservation																												.	.	.																																																	.	.
Alig confidence																												.	.	.													.																																				.	.
Template Conservation																																											.
Template Sequence		F	E	E	R	H	L	K	Y	I	S	Q	L	G	K	G	N	F	G	S	V	E	L	C	R	Y	D	P	L	G	D	N	T	G	A	L	V	A	V	K	Q	L	.	Q	H	S	G	P	D	Q	Q	R	D	F	Q	R	E	I	Q	I	L	K	A	L	H	S	D	F	I	V	K	Y	R	G	V	S	Y	G	P	G	R
Template Known Secondary structure				G	G	G											T	T										T	T	S	S	S		S									.	S	S																		T				T	T	B									S	S	S	S
Template Predicted Secondary structure																																											.
Template SS confidence
		817	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.		.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.
		201	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.			220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.
Predicted Secondary structure																					.	.																																																									.	.	.
Query SS confidence																					.	.																																																									.	.	.
Query Sequence		H	P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	.	.	K	K	N	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	.	.	.
Query Conservation																					.	.																																																									.	.	.
Alig confidence																					.	.																																																									.	.	.
Template Conservation
Template Sequence		Q	S	L	R	L	V	M	E	Y	L	P	S	G	C	L	R	D	F	L	Q	R	H	R	A	R	L	D	A	S	R	L	L	L	Y	S	S	Q	I	C	K	G	M	E	Y	L	G	S	R	R	C	V	H	R	D	L	A	A	R	N	I	L	V	E	S	E	A	H	V	K	I	A	D	F	G	L	A	K	L	L	P
Template Known Secondary structure												T	T		B									G	G	G																							T	T				S			S	G	G	G						T	T								T	T
Template Predicted Secondary structure
Template SS confidence
		896	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.
			276	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.										330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.
Predicted Secondary structure		.																																																							.	.	.	.	.	.	.	.	.
Query SS confidence		.																																																							.	.	.	.	.	.	.	.	.
Query Sequence		.	N	K	D	E	I	K	D	E	T	L	E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	.	.	.	.	.	.	.	.	.	L	T	K	I	Q	T	R	A	K	I	V	V	N	D	Y	R
Query Conservation		.																																																							.	.	.	.	.	.	.	.	.
Alig confidence		.																																															.								.	.	.	.	.	.	.	.	.
Template Conservation																																																	.
Template Sequence		L	D	K	D	Y	Y	V	V	R	E	P	G	Q	S	P	I	F	W	Y	A	P	E	S	L	S	D	N	I	F	S	R	Q	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	C	D	K	S	C	S	P	S	A	E	F	L	R	M	M	V	P	A	L	S	R	L	L	E	L	L	E	E	G	Q	R
Template Known Secondary structure		T	T		S					S	S				S		G	G	G																													T	.	T	T		G	G	G	S																						T	T
Template Predicted Secondary structure																																																	.
Template SS confidence
		976	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.		.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.
		346	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	K	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L	R	E	F
Query Conservation
Alig confidence																	.
Template Conservation																	.
Template Sequence		L	P	A	P	P	A	C	P	A	E	V	H	E	L	M	.	K	L	C	W	A	P	S	P	Q	D	R	P	S	F	S	A	L	G	P	Q	L	D	M	L
Template Known Secondary structure						T	T										.				T		S	S	G	G	G	S
Template Predicted Secondary structure																	.
Template SS confidence
		1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.		.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D