Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 236 Aligned Residues 245 % Identity 23% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.							.	.	190	.	.	.	.	.	.	.	.	.	200	.
Predicted Secondary structure																																																														.	.	.	.	.	.
Query SS confidence																																																														.	.	.	.	.	.
Query Sequence		H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	.	.	.	.	.	.	K	H	V	V	K	L	I	G	V	A	I	H	E	H
Query Conservation																																																														.	.	.	.	.	.
Alig confidence																								.															.	.																						.	.	.	.	.	.
Template Conservation																								.															.	.
Template Sequence		A	Y	R	Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	Y	.	D	H	K	V	H	Q	H	V	A	L	K	M	V	R	.	.	N	E	K	R	F	H	R	Q	A	A	E	E	I	R	I	L	E	H	L	R	K	Q	D	K	D	N	T	M	N	V	I	H	M	L	E	N	F	T	F	R	N
Template Known Secondary structure		T	T	T										S	S	S								.		T	T	T	T										.	.	S																				T	T		T	T	S		S		B										T	T
Template Predicted Secondary structure																								.															.	.
Template SS confidence
		146	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.		.	.	170	.	.	.	.	.	.	.	.	.	180	.			.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
		202	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.			.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.			.	.	.	.	.	270	.	.	.	.	.	.	.
Predicted Secondary structure																						.	.																																												.	.
Query SS confidence																						.	.																																												.	.
Query Sequence		P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	K	K	.	.	N	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	.	.	E	L	K	I	S	D	F	G	M	S	D	N	K
Query Conservation																						.	.																																												.	.
Alig confidence																						.	.																																												.	.
Template Conservation
Template Sequence		H	I	C	M	T	F	E	L	L	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L	Q	C	L	D	A	L	H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I	K	V	I	D	F	G	S	S	C	Y	E
Template Known Secondary structure													B								T	T	T																										T				S			S	G	G	G				S	S	T	T	S									T	T				T
Template Predicted Secondary structure
Template SS confidence
		223	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.
		278	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.
Predicted Secondary structure																																																																								.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																								.	.	.	.	.	.	.	.	.	.
Query Sequence		D	E	I	K	D	E	T	L	E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	T	K	I	Q	T	R	A	K	I	V	V	N	D	Y	R	M	K	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																																								.	.	.	.	.	.	.	.	.	.
Alig confidence													.	.	.																															.																										.	.	.	.	.	.	.	.	.	.
Template Conservation													.	.	.																															.
Template Sequence		H	Q	R	V	Y	T	I	Q	S	R	F	.	.	.	Y	R	A	P	E	V	I	L	G	A	R	Y	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	.	G	Y	P	L	L	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M	P	S	Q	K	L	L	D	A	S	K	R	A
Template Known Secondary structure		T									G	G	.	.	.	G								T	B				T																	.	S	S		S	S			S	S																						T	B	T	T
Template Predicted Secondary structure													.	.	.																															.
Template SS confidence
		303	.	.	.	.	.	.	310	.	.	.				.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.		.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.
																																														348	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.
Template Conservation																																																											.
Template Sequence		K	N	F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F	L	.	K	Q	C	L	E	W	D	P	A	V	R	M	T	P	G	Q	A	L	R
Template Known Secondary structure					B					B	T	T	S																T	T						S	T	T		S						T	T	T											.				T		S	S	T	T	T	S								T
Template Predicted Secondary structure																																																											.
Template SS confidence
		380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.		.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D