Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 125 Aligned Residues 240 % Identity 33% Template c3k54A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases. Resolution 1.94 Å

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		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	P	W	L	I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I	H	E	H
Query Conservation
Alig confidence																																.	.												.	.	.	.	.	.	.	.	.
Template Conservation																																.	.												.	.	.	.	.	.	.	.	.
Template Sequence		G	S	W	E	I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	.	.	G	Q	Y	D	V	A	I	K	M	I	K	.	.	.	.	.	.	.	.	.	E	F	I	E	E	A	K	V	M	M	N	L	S	H	E	K	L	V	Q	L	Y	G	V	C	T	K	Q	R
Template Known Secondary structure		G	G	G	B			G	G	G									S	T	T	S	S								T	.	.	T	T										.	.	.	.	.	.	.	.	.			T	T											T	T	B									S	S	S
Template Predicted Secondary structure																																.	.												.	.	.	.	.	.	.	.	.
Template SS confidence
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.			.	.	.	.	.	.	.	430	.	.	.										.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.
		202	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.			220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																				.	.
Query SS confidence																				.	.
Query Sequence		P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	.	.	K	K	N	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	N	K	D	E
Query Conservation																				.	.
Alig confidence																				.	.																																																								.	.	.	.	.
Template Conservation																																																																													.	.	.	.	.
Template Sequence		P	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y	L	E	S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K	V	S	D	F	G	F	P	.	.	.	.	.
Template Known Secondary structure		S									T	T										G	G	G																								T	T				S			S	G	G	G					T	T												.	.	.	.	.
Template Predicted Secondary structure																																																																													.	.	.	.	.
Template SS confidence
		469	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.
		280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	K	D	E	T	L	E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	T	K	I	Q	T	R	A	K	I	V	V	N	D	Y	R	M	K	M	P	D	G	T	H	P	T	V	A	D	V
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.																																																					.
Template Conservation		.	.	.	.	.	.	.	.	.	.																																																					.
Template Sequence		.	.	.	.	.	.	.	.	.	.	V	R	W	S	P	P	E	V	L	M	Y	S	K	F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	I	A	Q	.	G	L	R	L	Y	R	P	H	L	A	S	E	K	V	Y	T	I
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	G	G	G																													T	T	S			T	T	T	T	S											T	.	T							T	T	S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.																																																					.
Template SS confidence
												561	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.		.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L	R	E	F	Y	E	S	K
Query Conservation
Alig confidence			.
Template Conservation			.
Template Sequence		M	.	Y	S	C	W	H	E	K	A	D	E	R	P	T	F	K	I	L	L	S	N	I	L	D	V	M	D	E	E
Template Known Secondary structure			.			T	T		S	S	G	G	G	S
Template Predicted Secondary structure			.
Template SS confidence
		630		.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D