Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 81 Aligned Residues 262 % Identity 29% Template c3fupB_ PDB info PDB header:transferase Chain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 2.40 Å

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		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150				.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.
Predicted Secondary structure																															.	.	.
Query SS confidence																															.	.	.
Query Sequence		S	P	W	L	I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	.	.	.	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I
Query Conservation																															.	.	.
Alig confidence																															.	.	.																	.
Template Conservation																																																		.
Template Sequence		D	P	T	Q	F	E	E	R	H	L	K	F	L	Q	Q	L	G	K	G	N	F	G	S	V	E	M	C	R	Y	D	P	L	Q	D	N	T	G	E	V	V	A	V	K	K	L	Q	H	S	.	T	E	E	H	L	R	D	F	E	R	E	I	E	I	L	K	S	L	Q	H	D	N	I	V	K	Y	K	G	V	C	Y
Template Known Secondary structure			T	T				G	G	G											S	S										T	T	S	S	S											S			.																	T				T	T	B
Template Predicted Secondary structure																																																		.
Template SS confidence
		840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.		.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.
		199	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.			.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
Predicted Secondary structure																						.	.
Query SS confidence																						.	.
Query Sequence		H	E	H	P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	.	.	L	K	K	N	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	N
Query Conservation																						.	.
Alig confidence		.	.																			.	.
Template Conservation		.	.
Template Sequence		.	.	S	N	L	K	L	I	M	E	Y	L	P	Y	G	S	L	R	D	Y	L	Q	K	H	K	E	R	I	D	H	I	K	L	L	Q	Y	T	S	Q	I	C	K	G	M	E	Y	L	G	T	K	R	Y	I	H	R	D	L	A	T	R	N	I	L	V	E	N	E	N	R	V	K	I	G	D	F	G	L	T	K	V
Template Known Secondary structure		.	.											T	T		B					T	T	T	S	T	T	T																						T	T	T								G	G	G						T	T								T	T
Template Predicted Secondary structure		.	.
Template SS confidence
				919	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.
		277	.	.	280	.	.	.	.	.	.			.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.																.	.	330	.	.	.	.	.	.	.	.	.
Predicted Secondary structure												.	.																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence												.	.																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	D	E	I	K	D	E	T	L	E	.	.	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	G	L	T	K	I	Q	T	R	A	K	I
Query Conservation												.	.																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence												.	.																																				.						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																	.
Template Sequence		L	P	Q	D	K	E	K	V	K	E	P	G	E	S	P	I	F	W	Y	A	P	E	S	L	T	E	S	K	F	S	V	A	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	I	E	K	S	K	S	P	P	A	E	F	M	R	M	I	G	N	D	K	Q	G	Q	M	I	V	F	H	L	I	E	L
Template Known Secondary structure				T	T							S	S				G	G	G																														.	T	T		G	G	G	S											S				S	S
Template Predicted Secondary structure																																																	.
Template SS confidence
		1001	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.		.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.
		340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	V	N	D	Y	R	M	K	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L	R	E	F	Y	E	S
Query Conservation
Alig confidence																							.
Template Conservation																							.
Template Sequence		L	K	N	N	G	R	L	P	R	P	D	G	C	P	D	E	I	Y	M	I	M	.	T	E	C	W	N	N	N	V	N	Q	R	P	S	F	R	D	L	A	L	R	V	D	Q	I	R	D	Q
Template Known Secondary structure				T	T							T	T			T	T						.				T		S	S	G	G	G	S
Template Predicted Secondary structure																							.
Template SS confidence
		1082	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.		.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D