Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 80 Aligned Residues 257 % Identity 28% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

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		123	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.				.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																		.	.	.
Query SS confidence																																		.	.	.
Query Sequence		P	W	L	I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	.	.	.	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I	H
Query Conservation																																		.	.	.
Alig confidence																																		.	.	.													.	.	.	.	.
Template Conservation																																																	.	.	.	.	.
Template Sequence		P	T	H	F	E	K	R	F	L	K	R	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	P	H	.	.	.	.	.	I	A	D	L	K	K	E	I	E	I	L	R	N	L	Y	H	E	N	I	V	K	Y	K	G	I	C	T	E
Template Known Secondary structure		T	T	S			G	G	G											S	S										T	T	S	S	S		S												.	.	.	.	.													T				T	T	B
Template Predicted Secondary structure																																																	.	.	.	.	.
Template SS confidence
		867	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.						.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.
		200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.			.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.
Predicted Secondary structure																									.	.
Query SS confidence																									.	.
Query Sequence		E	H	P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	K	K	N	.	.	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	N	K
Query Conservation																									.	.
Alig confidence					.																				.	.
Template Conservation					.
Template Sequence		N	G	I	.	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	N	K	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K	G	M	D	Y	L	G	S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	S	E	H	Q	V	K	I	G	D	F	G	L	T	K	A	I
Template Known Secondary structure					.								T	T		B					T	G	G	G	T	T	T																							T	T				S			S	G	G	G						T	T								T	T
Template Predicted Secondary structure					.
Template SS confidence
		950	.	.		.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.
		278	.	280	.	.	.	.	.	.			.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.															.	330	.	.	.	.	.	.	.	.	.	340	.
Predicted Secondary structure											.	.																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence											.	.																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		D	E	I	K	D	E	T	L	E	.	.	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	L	T	K	I	Q	T	R	A	K	I	V	V
Query Conservation											.	.																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence											.	.																																				.							.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																.
Template Sequence		E	T	D	K	E	T	V	K	D	D	R	D	S	P	V	F	W	Y	A	P	E	C	L	M	Q	S	K	F	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	T	.	Y	C	D	S	D	S	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q	M	T	V	T	R	L	V	N	T	L	K
Template Known Secondary structure			T	T					S			T	T			G	G	G																													T	.	T	T		G	G	G												S			G	G	G
Template Predicted Secondary structure																																																.
Template SS confidence
		1029	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.		.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.
		342	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	D	Y	R	M	K	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L	R	E	F	Y	E
Query Conservation
Alig confidence																					.
Template Conservation																					.
Template Sequence		E	G	K	R	L	P	C	P	P	N	C	P	D	E	V	Y	Q	L	M	.	R	K	C	W	E	F	Q	P	S	N	R	T	S	F	Q	N	L	I	E	G	F	E	A	L	L	K
Template Known Secondary structure		T	T							T	T										.			T			S	S	G	G	G	S												T	T
Template Predicted Secondary structure																					.
Template SS confidence
		1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.		.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D