|   |   |
122 | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | |
. | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 |
| Predicted Secondary structure |   |
|
|  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | P | W | L | I | N | H | D | S | I | V | A | N | K | K | L | G | E | G | A | F | G | D | V | F | I | A | E | L | D | Q | G | G | K | Q | E | V | A | V | K | T | M | R | A | E | A | T | R | E | A | R | L | R | F | M | K | E | A | R | L | . |
M | R | K | Y | Q | H | K | H | V | V | K | L | I | G | V | A | I | H | E |
| Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   | . |
|   |   |
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   | . |   |   |   |
|
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
Q | N | F | E | V | K | A | D | D | L | E | P | I | M | E | L | G | R | G | A | Y | G | V | V | E | K | M | R | . |
H | V | P | S | G | Q | I | M | A | V | K | R | I | R | A | T | V | N | S | Q | E | Q | K | R | L | L | M | D | L | D | I | S | M | R | T | V | D | C | P | F | T | V | T | F | Y | G | A | L | F | R | E |
| Template Known Secondary structure |   |
|
|
|
|
|
| S | S |
|  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  | . |  | T | T | T | T |  |  |  |  |  |  |  |  |
| S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | T |
|
|  |  |  |  |  |  |
| S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
44 | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | |
. | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . |
|   |
|   |   |
201 | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | |
|
|
|
. | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | |
. | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
H | P | L | M | I | V | M | E | Y | C | P | N | G | S | L | L | S | H | . |
. |
. |
. |
L | K | K | N | K | V | S | L | I | E | K | L | R | F | T | T | E | A | A | D | G | I | A | Y | L | E | R | S | . |
K | C | I | H | R | D | I | A | A | R | N | C | L | L | S | A | K | N | E | L | K | I | S | D | F | G | M | S | D |
| Query Conservation |   |
  |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   | . |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
G | D | V | W | I | C | M | E | L | M | D | T | S | L | D | K | F | Y | K | Q | V | I | D | K | G | Q | T | I | P | E | D | I | L | G | K | I | A | V | S | I | V | K | A | L | E | H | L | H | S | K | L | S | V | I | H | R | D | V | K | P | S | N | V | L | I | N | A | L | G | Q | V | K | M | C | D | F | G | I | S | G |
| Template Known Secondary structure |   |
S |
|  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
| S |
|
| S | T | T |  |  |  |
| S | T | T |
|  |  |  |
|
|
| S |  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
123 | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
|   |
|   |   |
276 | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
|
|
|
. | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | |
. | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
N | K | D | E | I | K | D | E | T | L | E | K | V | P | I | K | W | L | A | P | E | T | . |
. |
. |
. |
M | Q | E | K | V | Y | T | H | K | T | D | I | W | T | F | G | V | L | V | W | E | I | Y | S | D | G | A | E | P | Y | P | G | L | T | . |
K | I | Q | T | R | A | K | I | V | V | N | D | Y | R | M | K | M | P | D |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Y | L | V | D | S | V | A | K | T | I | D | A | G | C | K | P | Y | M | A | P | E | R | I | N | P | E | L | N | Q | K | G | Y | S | V | K | S | D | I | W | S | L | G | I | T | M | I | E | L | A | I | . |
L | R | F | P | Y | D | S | W | G | T | P | F | Q | Q | L | K | Q | V | V | E | E | P | S | P | Q | L | P | A | D |
| Template Known Secondary structure |   |
 |  | S |
|  |  |  |  |  |  | S | S |
|
|
|
|
|
|
|  |  |  |  | S |
|
| T | T |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | T | S |
| S | S |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
|
| G | G |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . |
|   |
|   |   |
351 | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | T | H | P | T | V | A | D | V | V | T | G | T | C | W | Q | K | N | P | E | K | R | S | T | M | D | S | I | H | K | K | L | R | E | F | Y | E | S | K | K |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
| . |   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|
|
|   | . | . |
|
|   |   |   |   |   |   |
| Template Sequence |   |
K | F | S | A | E | F | V | D | F | T | . |
S | Q | C | L | K | K | N | S | K | E | R | P | T | Y | P | E | L | M | Q | . |
. |
H | P | F | F | T | L | H | E |
| Template Known Secondary structure |   |
G | S |
|  |  |  |  |  |  |  | . |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  | T | T | . | . | S |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  | . |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
| . | . |
|  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
282 | . | . | . | . | . | . | . | 290 | . | |
. | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | |
|
. | . | . | . | . | . | . | . |
|   |