Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 306 Aligned Residues 248 % Identity 18% Template c2vx3D_ PDB info PDB header:transferase Chain: D: PDB Molecule:dual specificity tyrosine-phosphorylation- regulated PDBTitle: crystal structure of the human dual specificity tyrosine-2 phosphorylation-regulated kinase 1a Resolution 2.40 Å

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		125	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.							.	.	.	.	.	.	.
Predicted Secondary structure																																																																					.	.	.	.	.	.
Query SS confidence																																																																					.	.	.	.	.	.
Query Sequence		L	I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	.	.	.	.	.	.	K	L	I	G	V	A	I
Query Conservation																																																																					.	.	.	.	.	.
Alig confidence																											.															.	.																										.	.	.	.	.	.
Template Conservation																											.															.	.
Template Sequence		E	K	W	M	D	R	Y	E	I	D	S	L	I	G	K	G	S	F	G	Q	V	V	K	A	Y	.	D	R	V	E	Q	E	W	V	A	I	K	I	I	K	.	.	N	K	K	A	F	L	N	Q	A	Q	I	E	V	R	L	L	E	L	M	N	K	H	D	T	E	M	K	Y	Y	I	V	H	L	K	R	H	F	M
Template Known Secondary structure					T	T	T											T	T								.		T	T	T	T										.	.	S	S																				S	S	S	S	G	G	G	G	B
Template Predicted Secondary structure																											.															.	.
Template SS confidence
		153	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.		.	.	180	.	.	.	.	.	.	.	.	.	190	.			.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.
		199	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.							.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.
Predicted Secondary structure																											.	.	.	.	.	.
Query SS confidence																											.	.	.	.	.	.
Query Sequence		H	E	H	P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	K	K	N	K	.	.	.	.	.	.	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G
Query Conservation																											.	.	.	.	.	.
Alig confidence																											.	.	.	.	.	.
Template Conservation
Template Sequence		F	R	N	H	L	C	L	V	F	E	M	L	S	Y	N	L	Y	D	L	L	R	N	T	N	F	R	G	V	S	L	N	L	T	R	K	F	A	Q	Q	M	C	T	A	L	L	F	L	A	T	P	E	L	S	I	I	H	C	D	L	K	P	E	N	I	L	L	C	N	P	K	R	S	A	I	K	I	V	D	F	G
Template Known Secondary structure			T	T												B								T	T	T																								S	T	T	T					S				G	G	G				S	S	T	T	S									T
Template Predicted Secondary structure
Template SS confidence
		230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.
		273	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.
Predicted Secondary structure																																																																							.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																							.	.	.	.	.	.	.	.	.	.	.
Query Sequence		M	S	D	N	K	D	E	I	K	D	E	T	L	E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	T	K	I	Q	T	R	A	K	I	V	V	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																																							.	.	.	.	.	.	.	.	.	.	.
Alig confidence																		.	.	.																															.																				.	.	.	.	.	.	.	.	.	.	.
Template Conservation																		.	.	.																															.
Template Sequence		S	S	C	Q	L	G	Q	R	I	Y	Q	I	Q	S	R	F	.	.	.	Y	R	S	P	E	V	L	L	G	M	P	Y	D	L	A	I	D	M	W	S	L	G	C	I	L	V	E	M	H	T	.	G	E	P	L	F	S	G	A	N	E	V	D	Q	M	N	K	I	V	E	V	L	G	I	P	P	A	H	I	L	D
Template Known Secondary structure		T				T	T									G	G	.	.	.	G							T	T					T																	.	S	S		S	S			S	S														S							T
Template Predicted Secondary structure																		.	.	.																															.
Template SS confidence
		310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.				.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.		.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
																																																		342	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	D	Y	R	M	K	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																				.
Template Conservation																																																																					.
Template Sequence		Q	A	P	K	A	R	K	F	F	E	K	L	P	D	G	T	W	N	L	K	K	T	K	R	E	Y	K	P	P	G	T	R	K	L	H	N	I	L	G	V	E	T	G	G	P	G	G	R	R	A	G	E	S	G	H	T	V	A	D	Y	L	K	F	K	D	L	I	.	L	R	M	L	D	Y	D	P	K	T	R	I
Template Known Secondary structure		T		T	T	G	G	G	T					T	T	S											S			T	T		S						T	T	T	T	T	T	S	G	G	G	T	T	T	T		T	T														.				T		S		T	T	T	S
Template Predicted Secondary structure																																																																					.
Template SS confidence
		387	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.		.	.	.	.	.	.	460	.	.	.	.	.
		374	.	.	.	.	.	380
Predicted Secondary structure
Query SS confidence
Query Sequence		T	M	D	S	I	H	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	P	Y	Y	A	L	Q
Template Known Secondary structure								T
Template Predicted Secondary structure
Template SS confidence
		469	470	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D