Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 292 Aligned Residues 258 % Identity 21% Template c2vagA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity protein kinase clk1; PDBTitle: crystal structure of di-phosphorylated human clk1 in2 complex with a novel substituted indole inhibitor Resolution 1.80 Å

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		125	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190							.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																				.	.	.	.	.	.
Query SS confidence																																																																				.	.	.	.	.	.
Query Sequence		L	I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	.	.	.	.	.	.	V	K	L	I	G	V	A	I
Query Conservation																																																																				.	.	.	.	.	.
Alig confidence																																										.	.																									.	.	.	.	.	.
Template Conservation																																										.	.
Template Sequence		D	V	L	S	A	R	Y	E	I	V	D	T	L	G	E	G	A	F	G	K	V	V	E	C	I	D	H	K	A	G	G	R	H	V	A	V	K	I	V	K	.	.	N	V	D	R	Y	C	E	A	A	R	S	E	I	Q	V	L	E	H	L	N	T	T	D	P	N	S	T	F	R	C	V	Q	M	L	E	W	F	E
Template Known Secondary structure					T	T	T											T	T									T	T	T	T	T										.	.	S	S																						T	T		T	T		B
Template Predicted Secondary structure																																										.	.
Template SS confidence
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.			.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.
		199	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.			220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
Predicted Secondary structure																							.	.
Query SS confidence																							.	.
Query Sequence		H	E	H	P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	.	.	K	K	N	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	N
Query Conservation																							.	.
Alig confidence																							.	.
Template Conservation
Template Sequence		H	H	G	H	I	C	I	V	F	E	L	L	G	L	S	T	Y	D	F	I	K	E	N	G	F	L	P	F	R	L	D	H	I	R	K	M	A	Y	Q	I	C	K	S	V	N	F	L	H	S	N	K	L	T	H	T	D	L	K	P	E	N	I	L	F	V	Q	S	D	Y	T	E	A	Y	N	K	R	D	E	R	T
Template Known Secondary structure			T	T												B								T	T	T																									T	T								G	G	G				S
Template Predicted Secondary structure
Template SS confidence
		233	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.
		277	.	.	280	.	.	.	.	.	.	.	.	.	290	.													.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.
Predicted Secondary structure																	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	D	E	I	K	D	E	T	L	E	K	V	P	I	K	.	.	.	.	.	.	.	.	.	.	.	.	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	T	K	I	Q	T	R	A	K	I	V	V	N	D	Y
Query Conservation																	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																	.	.	.	.	.	.	.	.	.	.	.	.																															.
Template Conservation																																																											.
Template Sequence		L	I	N	P	D	I	K	V	V	D	F	G	S	A	T	Y	D	D	E	H	H	S	T	L	V	R	H	Y	R	A	P	E	V	I	L	A	L	G	W	S	Q	P	C	D	V	W	S	I	G	C	I	L	I	E	Y	Y	L	.	G	F	T	V	F	P	T	H	D	S	K	E	H	L	A	M	M	E	R	I	L	G
Template Known Secondary structure			S										S	S				T	T	S				S					S							T	T	S			S	T																	.	S	S		S				S
Template Predicted Secondary structure																																																											.
Template SS confidence
		316	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.		.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.
		345	.	.																																											.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
Predicted Secondary structure					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		R	M	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L
Query Conservation					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.																				.	.
Template Conservation																																																												.																				.	.
Template Sequence		P	L	P	K	H	M	I	Q	K	T	R	K	R	K	Y	F	H	H	D	R	L	D	W	D	E	H	S	S	A	G	R	Y	V	S	R	A	C	K	P	L	K	E	F	M	L	S	Q	D	V	E	H	E	R	L	F	D	L	I	.	Q	K	M	L	E	Y	D	P	A	K	R	I	T	L	R	E	A	L	K	.	.
Template Known Secondary structure		S										S		G	G	G			T	T						T	T	S													G	G	G	G		S			S											.				T		S	S	T	T	T	S							T	T	.	.
Template Predicted Secondary structure																																																												.																				.	.
Template SS confidence
		397	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.		.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.
		383	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	E	F	Y	E	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	P	F	F	D	L
Template Known Secondary structure		S	G	G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		474	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D