Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 145 Aligned Residues 239 % Identity 24% Template c2r7bA_ PDB info PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor Resolution 2.70 Å

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		129	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.			.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.
Predicted Secondary structure																																									.	.
Query SS confidence																																									.	.
Query Sequence		D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	.	.	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I	H	E	H	P	L	M	I	V
Query Conservation																																									.	.
Alig confidence																							.																		.	.
Template Conservation																							.
Template Sequence		E	D	F	K	F	G	K	I	L	G	E	G	S	F	S	T	V	V	L	A	R	.	E	L	A	T	S	R	E	Y	A	I	K	I	L	E	K	R	H	I	I	K	E	N	K	V	P	Y	V	T	R	E	R	D	V	M	S	R	L	D	H	P	F	F	V	K	L	Y	F	T	F	Q	D	D	E	K	L	Y	F	G
Template Known Secondary structure		G	G											S	S								.		T	T	T																	T	T														T				T	T	B										S	S
Template Predicted Secondary structure																							.
Template SS confidence
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100		.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.
		207	.	.	210	.	.	.	.	.	.	.	.	.		220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.
Predicted Secondary structure															.
Query SS confidence															.
Query Sequence		M	E	Y	C	P	N	G	S	L	L	S	H	L	.	K	K	N	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	N	K	D	E	I	K	D	E	T	L
Query Conservation															.
Alig confidence															.																																																											.	.	.	.	.	.	.	.
Template Conservation																																																																										.	.	.	.	.	.	.	.
Template Sequence		L	S	Y	A	K	N	G	E	L	L	K	Y	I	R	K	I	G	S	F	D	E	T	C	T	R	F	Y	T	A	E	I	V	S	A	L	E	Y	L	H	G	K	G	I	I	H	R	D	L	K	P	E	N	I	L	L	N	E	D	M	H	I	Q	I	T	D	F	G	T	A	K	V	L	.	.	.	.	.	.	.	.
Template Known Secondary structure						T	T		B								S	S	S																							T	T								T	T	T					T	T	S								T	T					.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																																										.	.	.	.	.	.	.	.
Template SS confidence
		159	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
		286	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	T	K	I	Q	T	R	A	K	I	V	V	N	D	Y	R	M	K	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T	C	W
Query Conservation
Alig confidence																																						.																						.	.																.
Template Conservation																																						.																						.	.																.
Template Sequence		F	V	G	T	A	Q	Y	V	S	P	E	L	L	T	E	K	S	A	C	K	S	S	D	L	W	A	L	G	C	I	I	Y	Q	L	V	A	.	G	L	P	P	F	R	A	G	N	E	Y	L	I	F	Q	K	I	I	K	L	E	.	.	Y	D	F	P	E	K	F	F	P	K	A	R	D	L	V	.	E	K	L	L
Template Known Secondary structure						G	G	G								S	S																					.	S	S		S				S	S											T		.	.					S	S	S									.		T	T	S
Template Predicted Secondary structure																																						.																						.	.																.
Template SS confidence
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.		.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.			.	300	.	.	.	.	.	.	.	.	.	310	.	.	.		.	.	.	.
		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	L	D	A	T	K	R	L	G	C	E	E	M	E	G
Template Known Secondary structure			S	S	T	T	S	S	T	T	S	G	G	G	T	T
Template Predicted Secondary structure
Template SS confidence
		318	.	320	.	.	.	.	.	.	.	.	.	330	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D