Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 4 Aligned Residues 381 % Identity 30% Template c2h8hA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor Resolution 2.20 Å Model Dimensions (Å) X:61.943 Y:74.442 Z:45.915

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.					40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.			.	.	.	70	.	.	.	.	.
Predicted Secondary structure																																								.	.	.	.																												.	.
Query SS confidence																																								.	.	.	.																												.	.
Query Sequence		G	T	V	E	K	S	S	N	N	D	A	S	V	T	D	D	I	R	S	A	E	Y	Y	H	G	M	V	P	R	Q	D	A	E	G	F	L	K	R	.	.	.	.	E	G	D	F	L	V	R	K	T	E	Q	M	P	G	K	V	V	L	A	M	S	V	R	V	T	D	E	.	.	L	C	R	H	F	M	L	N	M
Query Conservation																																								.	.	.	.																												.	.
Alig confidence																																								.	.	.	.																												.	.
Template Conservation
Template Sequence		G	Q	T	G	Y	I	P	S	N	Y	V	A	P	S	D	S	I	Q	A	E	E	W	Y	F	G	K	I	T	R	R	E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	Y	C	L	S	V	S	D	F	D	N	A	K	G	L	N	V	K	H	Y	K	I	R	K
Template Known Secondary structure									G	G	G				T	T	S	G	G	G	S	T	T	B			S											T		T	T			T	T								S	S	S	T	T											T	T	T										B
Template Predicted Secondary structure
Template SS confidence
		127	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.
		76	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.							.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																													.	.	.	.	.	.
Query SS confidence																																													.	.	.	.	.	.
Query Sequence		D	P	T	S	N	K	F	Y	F	E	H	T	H	Q	E	S	T	I	S	E	L	I	N	W	H	M	T	T	K	T	P	I	S	A	A	S	G	A	K	I	R	R	P	.	.	.	.	.	.	M	E	R	S	P	W	L	I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E
Query Conservation																																													.	.	.	.	.	.
Alig confidence			.																																										.	.	.	.	.	.
Template Conservation			.
Template Sequence		L	.	D	S	G	G	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G	L	C	H	R	L	T	T	V	C	P	T	S	K	P	Q	T	Q	G	L	A	K	D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T
Template Known Secondary structure		.	.			S						T	T				S	S													T	T	S	S	S														S	S	S	S	T	T		S	B			G	G	G											S	S
Template Predicted Secondary structure			.
Template SS confidence
		207		.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.
		150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.				.	.	.
Predicted Secondary structure																																																																												.	.	.
Query SS confidence																																																																												.	.	.
Query Sequence		L	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I	H	E	H	P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	K	K	N	K	.	.	.	V	S	L
Query Conservation																																																																												.	.	.
Alig confidence				.	.																		.	.																											.																									.	.	.
Template Conservation				.	.																		.	.																											.
Template Sequence		W	N	.	.	G	T	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	.	.	E	A	F	L	Q	E	A	Q	V	M	K	K	L	R	H	E	K	L	V	Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L
Template Known Secondary structure			T	.	.	T	T										T	T	S	S			.	.																T	T	B									.	S	S	S									T	T								S					T	T
Template Predicted Secondary structure				.	.																		.	.																											.
Template SS confidence
		286	.			.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.			.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
		227	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.			.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.
Predicted Secondary structure																																																			.	.
Query SS confidence																																																			.	.
Query Sequence		I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	.	.	N	K	D	E	I	K	D	E	T	L	E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T
Query Conservation																																																			.	.
Alig confidence																																																			.	.
Template Conservation
Template Sequence		P	Q	L	V	D	M	A	A	Q	I	A	S	G	M	A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F	T
Template Known Secondary structure																					T	T				S			S	G	G	G					G	G	G							T	T	S	T	T	T								T	T		S	T	T	S		G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		361	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440
		305	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	T	K	I	Q	T	R	A	K	I	V	V	N	D	Y	R	M	K	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L	R	E
Query Conservation
Alig confidence																																						.																				.
Template Conservation																																						.																				.
Template Sequence		I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	.	R	G	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	L	M	.	C	Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D
Template Known Secondary structure																	T	T	T	T			S	S	T	T												.	T	T							T	T										.				T		S	S	G	G	G	S												T
Template Predicted Secondary structure																																						.																				.
Template SS confidence
		441	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.		.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.		.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.
		385	.	.	.	.	390
Predicted Secondary structure
Query SS confidence
Query Sequence		F	Y	E	S	K	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	F	T	S	T	E
Template Known Secondary structure		S	S				S
Template Predicted Secondary structure
Template SS confidence
		519	520	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D