Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 120 Aligned Residues 250 % Identity 30% Template c1xkkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016 Resolution 2.40 Å

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		126	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L	D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I	H	E	H	P	L	M	I
Query Conservation
Alig confidence																										.																	.	.	.	.																																	.
Template Conservation																										.																	.	.	.	.																																	.
Template Sequence		L	K	E	T	E	F	K	K	I	K	V	L	G	S	G	A	F	G	T	V	Y	K	G	L	.	W	I	P	V	K	I	P	V	A	I	K	E	L	R	E	K	.	.	.	.	A	N	K	E	I	L	D	E	A	Y	V	M	A	S	V	D	N	P	H	V	C	R	L	L	G	I	C	L	T	S	T	V	.	Q	L
Template Known Secondary structure				T	T	T											S	S								.																	.	.	.	.	T																	T	T	B									S	S	S		.
Template Predicted Secondary structure																										.																	.	.	.	.																																	.
Template SS confidence
		707	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730		.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.					.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.		.	780
		206	.	.	.	210	.	.	.	.	.	.	.	.	.			220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.
Predicted Secondary structure																.	.
Query SS confidence																.	.
Query Sequence		V	M	E	Y	C	P	N	G	S	L	L	S	H	L	.	.	K	K	N	K	V	S	L	I	E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	N	K	D	E	I	K	D	E
Query Conservation																.	.
Alig confidence																.	.																																																									.	.	.	.	.
Template Conservation																																																																										.	.	.	.	.
Template Sequence		I	T	Q	L	M	P	F	G	C	L	L	D	Y	V	R	E	H	K	D	N	I	G	S	Q	Y	L	L	N	W	C	V	Q	I	A	K	G	M	N	Y	L	E	D	R	R	L	V	H	R	D	L	A	A	R	N	V	L	V	K	T	P	Q	H	V	K	I	T	D	F	G	L	A	K	.	.	.	.	.	L	L	G
Template Known Secondary structure							T	T		B								T	S	S	S																							T	T				S				G	G	G						T	T								S				.	.	.	.	.		T	T
Template Predicted Secondary structure																																																																										.	.	.	.	.
Template SS confidence
		789	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860						.	.	.
		284	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	L	E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H	K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	T	K	I	Q	T	R	A	K	I	V	V	N	D	Y	R	M	K	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T
Query Conservation
Alig confidence																																																												.																			.
Template Conservation																																																												.																			.
Template Sequence		A	E	E	K	V	P	I	K	W	M	A	L	E	S	I	L	H	R	I	Y	T	H	Q	S	D	V	W	S	Y	G	V	T	V	W	E	L	M	T	F	G	S	K	P	Y	D	G	I	P	A	S	E	I	S	S	I	L	E	K	.	G	E	R	L	P	Q	P	P	I	C	T	I	D	V	Y	M	I	M	.	V	K
Template Known Secondary structure		T	T					T	T	T	S																												T	T	S			T	T	T	T	S		G	G	G								.	T							T	T	B									.
Template Predicted Secondary structure																																																												.																			.
Template SS confidence
		864	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.		.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.		940	.
		364	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L	R	E	F	Y	E	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		C	W	M	I	D	A	D	S	R	P	K	F	R	E	L	I	I	E	F	S	K	M	A	R	D
Template Known Secondary structure			T		S	S	G	G	G	S																S
Template Predicted Secondary structure
Template SS confidence
		950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D