Job Description Q22146 Confidence 100.00% Date Sat Apr 13 13:24:31 BST 2013 Rank 2 Aligned Residues 379 % Identity 31% Template c1oplA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase Resolution 3.42 Å Model Dimensions (Å) X:76.960 Y:72.419 Z:48.686

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.			.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																							.	.
Query SS confidence																																							.	.
Query Sequence		G	T	V	E	K	S	S	N	N	D	A	S	V	T	D	D	I	R	S	A	E	Y	Y	H	G	M	V	P	R	Q	D	A	E	G	F	L	K	.	.	R	E	G	D	F	L	V	R	K	T	E	Q	M	P	G	K	V	V	L	A	M	S	V	R	V	T	D	E	L	C	R	H	F	M	L	N	M	D	P	T	S
Query Conservation																																							.	.
Alig confidence																																							.	.																						.	.	.																.
Template Conservation																																																														.	.	.																.
Template Sequence		N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R	S	I	S	L	.	.	.	R	Y	E	G	R	V	Y	H	Y	R	I	N	T	A	S	.	D
Template Known Secondary structure		S							G	G	G				S	S	S	G	G	G	S	T	T														G	G	G			T	T								S	S	S	T	T							.	.	.			T	T											T	.	T
Template Predicted Secondary structure																																																														.	.	.																.
Template SS confidence
		125	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.				.	.	.	.	.	190	.	.	.	.	.	.	.	.	.		200
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.										.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150
Predicted Secondary structure																																								.	.	.	.	.	.	.	.	.
Query SS confidence																																								.	.	.	.	.	.	.	.	.
Query Sequence		N	K	F	Y	F	E	H	T	H	Q	E	S	T	I	S	E	L	I	N	W	H	M	T	T	K	T	P	I	S	A	A	S	G	A	K	I	R	R	.	.	.	.	.	.	.	.	.	P	M	E	R	S	P	W	L	I	N	H	D	S	I	V	A	N	K	K	L	G	E	G	A	F	G	D	V	F	I	A	E	L
Query Conservation																																								.	.	.	.	.	.	.	.	.
Alig confidence																																								.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W
Template Known Secondary structure		S				S	S	T	T	S		B	S	S									T	T			T	T	S	S	S										S					S	S	S		S	S	S	S			B			G	G	G							S	G	G	G	T	T	S	S
Template Predicted Secondary structure
Template SS confidence
		201	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
		151	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220				.	.	.	.	.	.	.
Predicted Secondary structure																																																																								.	.	.
Query SS confidence																																																																								.	.	.
Query Sequence		D	Q	G	G	K	Q	E	V	A	V	K	T	M	R	A	E	A	T	R	E	A	R	L	R	F	M	K	E	A	R	L	M	R	K	Y	Q	H	K	H	V	V	K	L	I	G	V	A	I	H	E	H	P	L	M	I	V	M	E	Y	C	P	N	G	S	L	L	S	H	L	K	.	.	.	K	N	K	V	S	L	I
Query Conservation																																																																								.	.	.
Alig confidence				.																		.	.																																																	.	.	.
Template Conservation				.																		.	.
Template Sequence		K	K	.	Y	S	L	T	V	A	V	K	T	L	K	E	D	T	M	E	V	.	.	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A	V
Template Known Secondary structure		G	G	.	G	T										S	S	S	S			.	.																T	T	B									S	S	S	S									T	T		B								S		T	T	T	S
Template Predicted Secondary structure				.																		.	.
Template SS confidence
		281	.		.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.			300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.
		228	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.			.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.
Predicted Secondary structure																																																		.	.
Query SS confidence																																																		.	.
Query Sequence		E	K	L	R	F	T	T	E	A	A	D	G	I	A	Y	L	E	R	S	K	C	I	H	R	D	I	A	A	R	N	C	L	L	S	A	K	N	E	L	K	I	S	D	F	G	M	S	D	.	.	N	K	D	E	I	K	D	E	T	L	E	K	V	P	I	K	W	L	A	P	E	T	M	Q	E	K	V	Y	T	H
Query Conservation																																																		.	.
Alig confidence																																																		.	.
Template Conservation
Template Sequence		V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I
Template Known Secondary structure																				T	T				S			S	G	G	G					G	G	G							T	T						T	T							T	T					G	G	G
Template Predicted Secondary structure
Template SS confidence
		358	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.
		306	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	T	D	I	W	T	F	G	V	L	V	W	E	I	Y	S	D	G	A	E	P	Y	P	G	L	T	K	I	Q	T	R	A	K	I	V	V	N	D	Y	R	M	K	M	P	D	G	T	H	P	T	V	A	D	V	V	T	G	T	C	W	Q	K	N	P	E	K	R	S	T	M	D	S	I	H	K	K	L	R	E	F
Query Conservation
Alig confidence																																						.																			.
Template Conservation																																						.																			.
Template Sequence		K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K	.	D	Y	R	M	E	R	P	E	G	C	P	E	K	V	Y	E	L	M	.	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M
Template Known Secondary structure																	T	T	S			S	S	T	T			T	T	T							T	.	T							T	T										.				T		S	S	G	G	G	S												T	S
Template Predicted Secondary structure																																						.																			.
Template SS confidence
		438	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.		.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.		.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.
		386	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	E	S	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	Q	E	S
Template Known Secondary structure			S	S	S
Template Predicted Secondary structure
Template SS confidence
		516	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D