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Job DescriptionQ9XXE5
Confidence100.00%DateSat Apr 13 12:56:17 BST 2013
Rank4Aligned Residues222
% Identity27%Templatec2h8hA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
Resolution2.20 Å
Model Dimensions (Å)X:73.790 Y:45.580 Z:47.024

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   910.........20.........30.... .....40.........50.........60.........70..... ....80..
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Query Sequence  QRPSIEKEPYYHGFLPREDVKTVLKN. . . . NGDFVIRISEPQAGSPRSNILSVMHCVPPMEEEIKHYVIKT. . KGDKIFI
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Template Sequence  PSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKG. . . AYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYIT
Template Known Secondary structure  TTSGGGSTTB

S

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TT

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   139140.........150.........160.........170.........180.. .......190.........200.........210.....
 
   83......90.........100 .........110.........120.........130.........140.........150....
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Query Sequence  EKVSFLSIPEMVEWHLTK. . . . . . . . KESVQKDVFLIKAISRQAWELDHDNIEPLKKLGEGAFGEVMMGTMKFRKGGKSV
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Template Sequence  SRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWN. . . . . GTT
Template Known Secondary structure  TTSS

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SSSSTT
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   216...220.........230.........240.........250.........260.........270.........280....... ..290
 
   155....160.........170.........180.........190.........200..... ....210.........220..... .
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Query Sequence  QVAIKQAKLSNLTKEQIKEFMGEARVMRSLSHPHVVRFYGVPRRRVNVALC. . . . . . RSLNEFLAKCHRKLRCATPF. . F
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Template Sequence  RVAIKTLKPGTMSPE. . . AFLQEAQVMKKLRHEKLVQLYAVVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDM
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   291........300..... ....310.........320.........330 .........340.........350.........360......
 
   227..230.........240..
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Query Sequence  VCMSVNWLSVLNELRV
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Template Sequence  AAQIASGMAYVERMNY
Template Known Secondary structure  TT
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   367..370.........380..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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