Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 131 Aligned Residues 261 % Identity 22% Template c4fvrA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structure of the jak2 pseudokinase domain mutant v617f (mg-2 atp-bound form) Resolution 2.00 Å

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		123	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.				.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																				.	.	.
Query SS confidence																																				.	.	.
Query Sequence		W	E	L	E	H	D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	.	.	.	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L
Query Conservation																																				.	.	.
Alig confidence																																				.	.	.													.	.
Template Conservation																																																			.	.
Template Sequence		H	K	I	R	N	E	D	L	I	F	N	E	S	L	G	Q	G	T	F	T	K	I	F	K	G	V	R	R	E	V	G	D	Y	G	Q	L	H	E	T	E	V	L	L	K	V	L	D	K	A	.	.	H	R	N	Y	S	E	S	F	F
Template Predicted Secondary structure																																																			.	.
Template SS confidence
		538	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.			.	.	.	590	.	.	.	.	.
		180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.		.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
Predicted Secondary structure																																													.
Query SS confidence																																													.
Query Sequence		A	E	A	R	T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	.	K	K	N	E	D	L	S	V	D	K	K	T	E	M	I	L
Query Conservation																																													.
Alig confidence																																													.
Template Conservation
Template Sequence		E	A	A	S	M	M	S	K	L	S	H	K	H	L	V	L	N	Y	G	V	C	F	C	G	D	E	N	I	L	V	Q	E	F	V	K	F	G	S	L	D	T	Y	L	K	K	N	K	N	C	I	N	I	L	W	K	L	E	V	A	K
Template Predicted Secondary structure
Template SS confidence
		596	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.		.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.						.	.	.	.	.	.	.	.	290	.	.
Predicted Secondary structure																										.																				.	.	.	.	.
Query SS confidence																										.																				.	.	.	.	.
Query Sequence		Q	A	A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	.	L	Y	T	D	G	K	V	K	I	S	D	F	G	L	T	R	N	G	T	.	.	.	.	.	V	Y	Q	I	K	P	N	T	K	S	P
Query Conservation																										.																				.	.	.	.	.
Alig confidence																										.																				.	.	.	.	.
Template Conservation
Template Sequence		Q	L	A	W	A	M	H	F	L	E	E	N	T	L	I	H	G	N	V	C	A	K	N	I	L	L	I	R	E	E	D	R	K	T	G	N	P	P	F	I	K	L	S	D	P	G	I	S	I	T	V	L	P	K	D	I	L	Q	E	R
Template Predicted Secondary structure
Template SS confidence
		656	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.
		293	.	.	.	.	.	.	300	.	.	.	.	.		.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.
Predicted Secondary structure															.
Query SS confidence															.
Query Sequence		I	R	W	L	A	I	E	T	I	K	T	M	I	.	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	V	A	T	Q	V	A	N	G	Y	R	M	P	P	Y
Query Conservation															.
Alig confidence															.																																								.	.
Template Conservation																																																							.	.
Template Sequence		I	P	W	V	P	P	E	C	I	E	N	P	K	N	L	N	L	A	T	D	K	W	S	F	G	T	T	L	W	E	I	C	S	G	G	D	K	P	L	S	A	L	D	S	Q	R	K	L	Q	F	Y	E	D	.	.	R	H	Q	L	P
Template Predicted Secondary structure																																																							.	.
Template SS confidence
		716	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.			.	770	.	.	.
		352	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	H	A	Q	A	E	I	Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I	L	Q	R	V	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	P	K	A	A	E	L	A	N	L	I	N	N	C	M	D	Y	E	P	D	H	R	P	S	F	R	A	I	I	R	D	L	N	S	L	F
Template Predicted Secondary structure
Template SS confidence
		774	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D