Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 7 Aligned Residues 368 % Identity 30% Template c4fl2A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch Resolution 2.19 Å Model Dimensions (Å) X:73.421 Y:94.089 Z:52.051

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		7	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.					.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.
Predicted Secondary structure																															.	.	.	.
Query SS confidence																															.	.	.	.
Query Sequence		P	S	E	V	S	N	A	T	I	D	K	E	L	Y	Y	H	G	L	L	P	S	E	D	V	R	Q	L	L	S	.	.	.	.	N	N	G	D	F	L	L	R	S	S	E	P	E	P	G	S	P	R	T	H	I	L	S	V	M	F	N
Query Conservation																															.	.	.	.
Alig confidence																															.	.	.	.												.					.	.	.
Template Conservation																																														.					.	.	.
Template Sequence		E	K	L	I	A	T	T	A	H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	.	N	N	G	S	.	.	.	Y	A	L	C	L	L	H	E
Template Known Secondary structure						T	T	S		G	G	G	S	T	T	B			S												S	S	S			T	T									.	T	T	T		.	.	.								T
Template Predicted Secondary structure																																														.					.	.	.
Template SS confidence
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.		.	200	.	.				.	.	.	.	.	.	.	210
		63	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.
Predicted Secondary structure																			.																																							.	.	.	.
Query SS confidence																			.																																							.	.	.	.
Query Sequence		N	R	L	D	D	I	N	S	I	K	H	F	V	V	N	F	V	.	D	G	K	Y	F	I	N	D	K	M	S	F	P	S	I	Q	K	M	L	G	T	Y	Q	R	N	N	T	E	I	K	E	G	C	M	L	V	N	P	.	.	.	.
Query Conservation																			.																																							.	.	.	.
Alig confidence				.	.	.	.	.	.										.																																							.	.	.	.
Template Conservation				.	.	.	.	.	.
Template Sequence		G	K	.	.	.	.	.	.	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	T
Template Known Secondary structure		T		.	.	.	.	.	.										T	T	S				S	T	T				B	S	S									T	T	B		T	T	S	S	S				S	B				S
Template Predicted Secondary structure				.	.	.	.	.	.
Template SS confidence
		211	.							.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.
																118	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.									.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	R	R	Q	F	W	E	L	E	H	D	Q	I	T	I	H	K	K	.	.	.	.	.	.	.	.	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		Q	R	E	A	L	P	M	D	T	E	V	Y	E	S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V
Template Known Secondary structure			T	T			G	G	G	S	G	G	G	S		G	G	G	S	T	T	S				S	S	S	B			G	G	G												T	T											T	T
Template Predicted Secondary structure
Template SS confidence
		337	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.
		156	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L	A	E	A	R	T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N
Query Conservation
Alig confidence		.	.																																												.
Template Conservation		.	.																																												.
Template Sequence		.	.	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L
Template Known Secondary structure		.	.										S	G	G	G		G	G	G																	T	T	B								.		S	S	S									T	T
Template Predicted Secondary structure		.	.																																												.
Template SS confidence
				397	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.		440	.	.	.	.	.	.	.	.	.	450	.	.	.
		216	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.		.	.	.	.	.	270	.	.	.	.
Predicted Secondary structure																																																			.
Query SS confidence																																																			.
Query Sequence		G	A	L	D	S	F	L	K	K	N	E	D	L	S	V	D	K	K	T	E	M	I	L	Q	A	A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	L	Y	.	T	D	G	K	V	K	I	S	D	F
Query Conservation																																																			.
Alig confidence																																																			.
Template Conservation
Template Sequence		G	P	L	N	K	Y	L	Q	Q	N	R	H	V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F
Template Known Secondary structure			B									T	T	S																						T	T				S			S	G	G	G						T	T							T
Template Predicted Secondary structure
Template SS confidence
		454	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.
		275	.	.	.	.	280	.	.	.					.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330
Predicted Secondary structure											.	.	.	.
Query SS confidence											.	.	.	.
Query Sequence		G	L	T	R	N	G	T	V	Y	.	.	.	.	Q	I	K	P	N	T	K	S	P	I	R	W	L	A	I	E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y
Query Conservation											.	.	.	.
Alig confidence											.	.	.	.
Template Conservation
Template Sequence		G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y
Template Known Secondary structure		T					T	T								S		B	T	T	B		G	G	G	G																													T	T	T			S	S
Template Predicted Secondary structure
Template SS confidence
		514	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.
		331	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	G	M	K	P	A	D	V	A	T	Q	V	A	N	G	Y	R	M	P	P	Y	P	H	A	Q	A	E	I	Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I	L	Q	R	V	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y	Y
Template Known Secondary structure		T	T												T	T							T	T													T		S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		574	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D