Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 84 Aligned Residues 261 % Identity 26% Template c4e1zA_ PDB info PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor Resolution 2.50 Å

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		124	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	L	E	H	D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L	A	E	A	R
Query Conservation
Alig confidence																																															.
Template Conservation																																															.
Template Sequence		V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	E	G	.	C	G	P	Q	L	R	S	G	W	Q	R	E	I	E
Template Known Secondary structure		B			G	G	G											S	S										T	T			S	S											T	T	.
Template Predicted Secondary structure																																															.
Template SS confidence
		887	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.		.	.	.	.	.	.	.	.	940	.	.	.	.	.
		184	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	K	K	N	E	D	L	S	V	D	K	K	T	E	M	I	L	Q	A	A	W	G
Query Conservation
Alig confidence																																											.	.
Template Conservation																																											.	.
Template Sequence		I	L	R	T	L	Y	H	E	H	I	V	K	Y	K	G	C	C	E	D	K	S	V	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	R	H	.	.	C	V	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G
Template Known Secondary structure									T	T	B																				T	T							G	G	G	S	.	.
Template Predicted Secondary structure																																											.	.
Template SS confidence
		946	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.			.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.
		244	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.		.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.					.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
Predicted Secondary structure																					.																					.	.	.	.
Query SS confidence																					.																					.	.	.	.
Query Sequence		L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	.	L	Y	T	D	G	K	V	K	I	S	D	F	G	L	T	R	N	G	T	V	.	.	.	.	Y	Q	I	K	P	N	T	K	S	P	I	R	W	L	A	I
Query Conservation																					.																					.	.	.	.
Alig confidence																					.																					.	.	.	.
Template Conservation
Template Sequence		M	A	Y	L	H	A	Q	H	Y	I	H	R	A	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A	V	P	E	G	H	E	Y	Y	R	V	R	E	D	G	D	S	P	V	F	W	Y	A	P
Template Known Secondary structure								T	T				S			S	G	G	G					G	G	G								T	T						T	T		S								S	S	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		1007	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.
		299	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.																.	.	.	.	.	.	.	.	340	.	.	.
Predicted Secondary structure																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	M	K	P	A	D	V	A	T	Q	V	A
Query Conservation																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																												.							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																												.
Template Sequence		E	C	L	K	E	C	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	Y	C	D	S	N	Q	S	P	H	T	K	F	T	E	L	I	G	H	T	Q	G	Q	M	T	V	L	R	L	T	E	L	L	E
Template Known Secondary structure						S																					T	.	T	T		T	T	S	S											S
Template Predicted Secondary structure																												.
Template SS confidence
		1067	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.
		344	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	G	Y	R	M	P	P	Y	P	H	A	Q	A	E	I	Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I	L	Q	R	V	T	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	G	E	R	L	P	R	P	D	R	C	P	C	E	I	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	Q	N	L	V	P	I	L	Q	T	A	Q	E
Template Known Secondary structure			T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1126	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D