Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 74 Aligned Residues 258 % Identity 30% Template c3v5qB_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models Resolution 2.20 Å

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		123	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.		.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.
Predicted Secondary structure																					.
Query SS confidence																					.
Query Sequence		W	E	L	E	H	D	Q	I	T	I	H	K	K	L	G	E	G	A	F	.	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L	A	E
Query Conservation																					.
Alig confidence																					.								.	.	.	.																	.	.
Template Conservation																													.	.	.	.																	.	.
Template Sequence		Q	H	I	K	R	R	D	I	V	L	K	R	E	L	G	F	K	V	F	L	A	E	C	Y	N	L	S	.	.	.	.	P	T	K	D	K	M	L	V	A	V	K	A	L	K	D	P	.	.	T	L	A	A	R	K	D	F	Q	R	E
Template Known Secondary structure						G	G	G																		S			.	.	.	.	S	S	S	S											S		.	.
Template Predicted Secondary structure																													.	.	.	.																	.	.
Template SS confidence
		531	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.					.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.			.	.	.	.	.	.	580	.	.	.	.
		182	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.		.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Predicted Secondary structure																																														.
Query SS confidence																																														.
Query Sequence		A	R	T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	K	K	N	.	E	D	L	S	V	D	K	K	T	E	M	I	L	Q	A
Query Conservation																																														.
Alig confidence																								.	.																					.
Template Conservation																								.	.
Template Sequence		A	E	L	L	T	N	L	Q	H	E	H	I	V	K	F	Y	G	V	C	G	D	P	.	.	L	I	M	V	F	E	Y	M	K	H	G	D	L	N	K	F	L	R	A	H	G	P	E	L	G	L	S	Q	M	L	H	I	A	S	Q	I
Template Known Secondary structure											T	T	B											.	.									T	T									T	T
Template Predicted Secondary structure																								.	.
Template SS confidence
		589	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610			.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.		.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																								.
Query SS confidence																								.
Query Sequence		A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	.	L	Y	T	D	G	K	V	K	I	S	D	F	G	L	T	R	N	G	T	V	Y	Q	I	K	P	N	T	K	S	P	I	R	W	L	A	I	E
Query Conservation																								.
Alig confidence																								.																		.	.	.
Template Conservation																																										.	.	.
Template Sequence		A	S	G	M	V	Y	L	A	S	Q	H	F	V	H	R	D	L	A	T	R	N	C	L	V	G	A	N	L	L	V	K	I	G	D	F	G	M	D	V	Y	.	.	.	S	T	D	Y	Y	R	T	M	L	P	I	R	W	M	P	P	E
Template Known Secondary structure											T	T				S			S	G	G	G					G	G	G												S	.	.	.	G	G	G		B				B		G	G	G
Template Predicted Secondary structure																																										.	.	.
Template SS confidence
		664	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.				.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
		300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	V	A	T	Q	V	A	N	G	Y	R	M	P	P	Y	P	H	A	Q	A	E	I	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	I	M	Y	R	K	F	T	T	E	S	D	V	W	S	F	G	V	I	L	W	E	I	F	T	Y	G	K	Q	P	W	F	Q	L	S	N	T	E	V	I	E	C	I	T	Q	G	R	V	L	E	R	P	R	V	C	P	K	E	V	Y
Template Known Secondary structure																									T	T	T	S			T	T	T	T	S												T							T	T
Template Predicted Secondary structure
Template SS confidence
		741	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I	L	Q	R	V	T	E	T	P	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	V	M	L	G	C	W	Q	R	E	P	Q	Q	R	L	N	I	K	E	I	Y	K	I	L	H	A	L	G	K	A	T	P
Template Known Secondary structure										S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		801	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D