Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 302 Aligned Residues 248 % Identity 23% Template c3ttjA_ PDB info PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:mitogen-activated protein kinase 10; PDBTitle: crystal structure of jnk3 complexed with cc-359, a jnk inhibitor for2 the prevention of ischemia-reperfusion injury Resolution 2.10 Å

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		117	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	I	R	R	Q	F	W	E	L	E	H	D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K
Query Conservation
Alig confidence												.																						.	.	.	.
Template Conservation												.																						.	.	.	.
Template Sequence		S	V	E	V	S	T	F	T	V	L	.	K	R	Y	Q	N	L	K	P	I	G	S	G	A	Q	G	I	V	C	A	A	Y	.	.	.	.	D	A	V	L	D	R	N	V	A	I	K	K	L	S	R	P	F	Q	N	Q	T	H	A	K
Template Known Secondary structure												.	T	T											S	S								.	.	.	.		T	T	T	T										S	G	G	G	S
Template Predicted Secondary structure												.																						.	.	.	.
Template SS confidence
		50	.	.	.	.	.	.	.	.	.		60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80					.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.
		177	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.							.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
Predicted Secondary structure																												.	.	.	.	.	.
Query SS confidence																												.	.	.	.	.	.
Query Sequence		D	F	L	A	E	A	R	T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	.	.	.	.	.	.	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	K	K	N	E	D	L	S	V
Query Conservation																												.	.	.	.	.	.
Alig confidence																												.	.	.	.	.	.																								.	.	.
Template Conservation																																																									.	.	.
Template Sequence		R	A	Y	R	E	L	V	L	M	K	C	V	N	H	K	N	I	I	S	L	L	N	V	F	T	P	Q	K	T	L	E	E	F	Q	D	V	Y	L	V	M	E	L	M	D	A	N	L	C	Q	V	I	Q	M	E	L	.	.	.	D	H
Template Known Secondary structure																T	T	B				S					S			S	T	T	T												S								T	S			.	.	.
Template Predicted Secondary structure																																																									.	.	.
Template SS confidence
		107	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.				.	.
		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.		270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																									.
Query SS confidence																																									.
Query Sequence		D	K	K	T	E	M	I	L	Q	A	A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	L	Y	T	D	G	K	V	.	K	I	S	D	F	G	L	T	R	N	G	T	V	Y	Q	I	K	P	N	T
Query Conservation																																									.
Alig confidence																																									.														.	.	.	.	.	.	.
Template Conservation																																																							.	.	.	.	.	.	.
Template Sequence		E	R	M	S	Y	L	L	Y	Q	M	L	C	G	I	K	H	L	H	S	A	G	I	I	H	R	D	L	K	P	S	N	I	V	V	K	S	D	C	T	L	K	I	L	D	F	G	L	A	S	F	M	M	V	.	.	.	.	.	.	.
Template Known Secondary structure																					T	T								G	G	G					T	T	S																.	.	.	.	.	.	.
Template Predicted Secondary structure																																																							.	.	.	.	.	.	.
Template SS confidence
		164	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.
		290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.
Predicted Secondary structure																																																								.	.	.	.	.	.
Query SS confidence																																																								.	.	.	.	.	.
Query Sequence		K	S	P	I	R	W	L	A	I	E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	V	A	T	Q	V	A	.	.	.	.	.	.
Query Conservation																																																								.	.	.	.	.	.
Alig confidence		.	.																																		.																			.	.	.	.	.	.
Template Conservation		.	.																																		.
Template Sequence		.	.	T	R	Y	Y	R	A	P	E	V	I	L	G	M	G	Y	K	E	N	V	D	I	W	S	V	G	C	I	M	G	E	M	V	R	.	H	K	I	L	F	P	G	R	D	Y	I	D	Q	W	N	K	V	I	E	Q	L	G	T	P
Template Known Secondary structure		.	.			T	T							T	T					T	T																.	S	S		S	S			S	S														S
Template Predicted Secondary structure		.	.																																		.
Template SS confidence
				226	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.		.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.
																																					344	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	G	Y	R	M	P	P	Y	P	H	A	Q	A	E	I	Q	T	M	M	A	R	C	N	A	E
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		C	P	E	F	M	K	K	L	Q	P	T	V	R	N	Y	V	E	N	R	P	K	Y	A	G	L	T	F	P	K	L	F	P	D	S	L	F	P	A	D	S	E	H	N	K	L	K	A	S	Q	A	R	D	L	L	S	K	M	L	V	I
Template Known Secondary structure							T	T	S									T	T	S												S		G	G	G	S			S	S																		S		S
Template Predicted Secondary structure
Template SS confidence
		283	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.
		369	370	.	.	.	.	.	.	.	.	.	380	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	P	N	D	R	P	S	M	A	E	I	A	E	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	P	A	K	R	I	S	V	D	D	A	L	Q	H
Template Known Secondary structure		S	T	T	T	S								T	S
Template Predicted Secondary structure
Template SS confidence
		343	.	.	.	.	.	.	350	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D