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Job DescriptionQ22245
Confidence100.00%DateSun Jun 30 11:14:08 BST 2013
Rank209Aligned Residues231
% Identity25%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   123......130.........140.........150.........160.........170.........180..
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Query Sequence  WELEHDQITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIKDFLAEA
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVK. . . . EKATGRYYAMKILK. . . . . . . . . KEVIVAN
Template Known Secondary structure  T


TTSTT....TTT

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   112.......120.........130....... ..140.........150. .......
 
   183......190.........200.........210.........220.........230.........240..
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Query Sequence  RTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVNGALDSFLKKNEDLSVDKKTEMILQAAW
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Template Sequence  RVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVS
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   200.........210.........220.........230.........240.........250.........
 
   243......250 .........260.. .......270.........280.........290.........300
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Query Sequence  GLEYIHGK. PMLHRDIAARNC. LYTDGKVKISDFGLTRNGTVYQIKPNTKSPIRWLAIET
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Template Sequence  ALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKE. . . . . . . . . . . . . PEYLAPEV
Template Known Secondary structure  TS







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   260.........270.........280.........290........ .300......
 
   301........310.........320.........330.........340.........350.........360
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Query Sequence  IKTMICSEKTDVWAYGVLCWEIFNNAAEPYPGMKPADVATQVANGYRMPPYPHAQAEIQT
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Template Sequence  LEDNDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKS
Template Known Secondary structure  TT



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   321........330.........340.... .....350.........360..... ....370........
 
   361........370... ......380.
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Query Sequence  MMARCNAENPNDR. . . . . PSMAEIAE
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Template Sequence  LLSGLLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure  T
SSTTTSTT
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   379380.........390.........400....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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