Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 218 Aligned Residues 248 % Identity 25% Template c3mtfB_ PDB info PDB header:transferase Chain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor Resolution 2.15 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L	A	E	A	R	T	M	R	K
Query Conservation
Alig confidence																									.	.	.	.	.	.														.	.	.
Template Conservation																									.	.	.	.	.	.														.	.	.
Template Sequence		R	D	I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G	S	W	Q	.	.	.	.	.	.	G	E	N	V	A	V	K	I	F	S	S	R	D	.	.	.	E	K	S	W	F	R	E	T	E	L	Y	N	T	V	M
Template Known Secondary structure		T	T											T	T									T	.	.	.	.	.	.	T										G	G	G	.	.	.														S
Template Predicted Secondary structure																									.	.	.	.	.	.														.	.	.
Template SS confidence
		206	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.							.	230	.	.	.	.	.	.	.	.	.	240	.				.	.	.	.	.	.	.	.	250	.	.	.	.	.	.
		188	.	190	.	.	.	.	.	.	.	.	.					200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.
Predicted Secondary structure														.	.	.	.
Query SS confidence														.	.	.	.
Query Sequence		L	G	H	Q	N	I	I	K	F	Y	G	V	.	.	.	.	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	K	K	N	E	D	L	S	V	D	K	K	T	E	M	I	L	Q	A	A	W	G
Query Conservation														.	.	.	.
Alig confidence														.	.	.	.																										.
Template Conservation																																											.
Template Sequence		L	R	H	E	N	I	L	G	F	I	A	S	D	M	T	S	R	H	S	S	T	Q	L	W	L	I	T	H	Y	H	E	M	G	S	L	Y	D	Y	L	Q	L	.	T	T	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G
Template Known Secondary structure					T	T	B												T	T												T	T		B								.			B
Template Predicted Secondary structure																																											.
Template SS confidence
		257	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.		.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.
		244	.	.	.	.	.	250	.	.									.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.		270	.	.	.	.	.	.	.	.	.						280	.	.	.	.	.	.	.	.	.
Predicted Secondary structure											.	.	.	.	.	.	.	.																		.											.	.	.	.	.
Query SS confidence											.	.	.	.	.	.	.	.																		.											.	.	.	.	.
Query Sequence		L	E	Y	I	H	G	K	P	M	.	.	.	.	.	.	.	.	L	H	R	D	I	A	A	R	N	C	L	Y	T	D	G	K	V	.	K	I	S	D	F	G	L	T	R	N	.	.	.	.	.	G	T	V	Y	Q	I	K	P	N	T
Query Conservation											.	.	.	.	.	.	.	.																		.											.	.	.	.	.
Alig confidence											.	.	.	.	.	.	.	.																		.											.	.	.	.	.
Template Conservation
Template Sequence		L	A	H	L	H	I	E	I	F	G	T	Q	G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V	K	K	N	G	Q	C	C	I	A	D	L	G	L	A	V	M	H	S	Q	S	T	N	Q	L	D	V	G	N	N	P	R
Template Known Secondary structure							S		B		S	T	T		B						S			S	G	G	G					T	T	S								T	T						T	T	T	T
Template Predicted Secondary structure
Template SS confidence
		316	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.
		290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.							.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.
Predicted Secondary structure																		.	.	.	.	.	.																															.	.	.	.	.	.	.	.
Query SS confidence																		.	.	.	.	.	.																															.	.	.	.	.	.	.	.
Query Sequence		K	S	P	I	R	W	L	A	I	E	T	I	K	T	M	I	.	.	.	.	.	.	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	.	.	.	.	.	.	.	.
Query Conservation																		.	.	.	.	.	.																															.	.	.	.	.	.	.	.
Alig confidence																		.	.	.	.	.	.																				.											.	.	.	.	.	.	.	.
Template Conservation																																											.
Template Sequence		V	G	T	K	R	Y	M	A	P	E	V	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E	V	A	R	.	R	M	V	S	N	G	I	V	E	D	Y	K	P	P	F	Y	D	V
Template Known Secondary structure					G	G	G							T	T				T	T																						T	.	T	B		B	T	T	B							T	T	T	T	T
Template Predicted Secondary structure																																											.
Template SS confidence
		376	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.		.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.
									336	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.							.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
Predicted Secondary structure		.	.	.	.	.	.	.																			.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.																			.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	A	D	V	A	T	Q	V	A	N	G	Y	R	M	P	P	Y	P	H	.	.	.	.	.	.	A	Q	A	E	I	Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I
Query Conservation		.	.	.	.	.	.	.																			.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.																			.	.	.	.	.	.
Template Conservation
Template Sequence		V	P	N	D	P	S	F	E	D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K	L	M	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K	T
Template Known Secondary structure		S		S	S											T	T	S								G	G	G	G	G	S																S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		435	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.
		383	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	Q	R	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	T	K	I
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		495	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D