Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 232 Aligned Residues 240 % Identity 22% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L	A	E	A	R	T	M	R	K	L	G
Query Conservation
Alig confidence																					.	.	.	.															.	.	.
Template Conservation																					.	.	.	.															.	.	.
Template Sequence		Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	Y	.	.	.	.	D	H	K	V	H	Q	H	V	A	L	K	M	V	R	.	.	.	N	E	K	R	F	H	R	Q	A	A	E	E	I	R	I	L	E	H	L	R
Template Known Secondary structure											S	S	S								.	.	.	.		T	T	T	T										.	.	.	S
Template Predicted Secondary structure																					.	.	.	.															.	.	.
Template SS confidence
		149	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.					.	.	170	.	.	.	.	.	.	.	.	.	180	.				.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.
		190							.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.			.	.	230	.	.	.	.	.	.	.	.	.	240	.
Predicted Secondary structure			.	.	.	.	.	.																																						.	.
Query SS confidence			.	.	.	.	.	.																																						.	.
Query Sequence		H	.	.	.	.	.	.	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	K	K	N	E	D	.	.	L	S	V	D	K	K	T	E	M	I	L	Q	A	A
Query Conservation			.	.	.	.	.	.																																						.	.
Alig confidence			.	.	.	.	.	.																								.														.	.
Template Conservation																																.
Template Sequence		K	Q	D	K	D	N	T	M	N	V	I	H	M	L	E	N	F	T	F	R	N	H	I	C	M	T	F	E	L	L	.	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L
Template Known Secondary structure		T	T		T	T	S		S		B										T	T										.			B								T	T	T
Template Predicted Secondary structure																																.
Template SS confidence
		202	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.		.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.				.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
Predicted Secondary structure																													.	.	.
Query SS confidence																													.	.	.
Query Sequence		W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	L	Y	T	D	G	K	.	.	.	V	K	I	S	D	F	G	L	T	R	N	G	T	V	Y	Q	I	K	P	N	T	K	S	P	I	R	W	L	A	I
Query Conservation																													.	.	.
Alig confidence																													.	.	.																						.	.	.
Template Conservation																																																					.	.	.
Template Sequence		Q	C	L	D	A	L	H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I	K	V	I	D	F	G	S	S	C	Y	E	H	Q	R	V	Y	T	I	Q	S	.	.	.	R	F	Y	R	A	P
Template Known Secondary structure											T				S			S	G	G	G				S	S	T	T	S									T	T				T	T									.	.	.	G	G	G
Template Predicted Secondary structure																																																					.	.	.
Template SS confidence
		261	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.				.	.	.	.	.	.
		299	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																					.	.	.	.	.	.	.	.	.
Query SS confidence																																																					.	.	.	.	.	.	.	.	.
Query Sequence		E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	V	A	T	Q	V	A	N	G	Y	R	M	P	.	.	.	.	.	.	.	.	.
Query Conservation																																																					.	.	.	.	.	.	.	.	.
Alig confidence																												.																									.	.	.	.	.	.	.	.	.
Template Conservation																												.
Template Sequence		E	V	I	L	G	A	R	Y	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	.	G	Y	P	L	L	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M	P	S	Q	K	L	L	D	A	S	K
Template Known Secondary structure						T	B				T																	.	S	S		S	S			S	S																						T	B	T
Template Predicted Secondary structure																												.
Template SS confidence
		319	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.		.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.
																																																350	.	.	.	.	.	.	.	.	.	360	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	Y	P	H	A	Q	A	E	I	Q	T	M	M	A
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		R	A	K	N	F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F	L	K
Template Known Secondary structure		T					B					B	T	T	S																T	T						S	T	T		S						T	T	T
Template Predicted Secondary structure
Template SS confidence
		378	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.
		364	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	C	L	E	W	D	P	A	V	R	M	T	P	G	Q	A	L	R
Template Known Secondary structure				T		S	S	T	T	T	S								T
Template Predicted Secondary structure
Template SS confidence
		441	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D