Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 121 Aligned Residues 240 % Identity 35% Template c3k54A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases. Resolution 1.94 Å

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		121	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	F	W	E	L	E	H	D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L	A
Query Conservation
Alig confidence																																.	.	.	.	.											.	.	.	.	.	.	.	.	.	.
Template Conservation																																.	.	.	.	.											.	.	.	.	.	.	.	.	.	.
Template Sequence		G	S	W	E	I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	.	.	.	.	.	G	Q	Y	D	V	A	I	K	M	I	.	.	.	.	.	.	.	.	.	.	K	E	F	I	E
Template Known Secondary structure		G	G	G	B			G	G	G									S	T	T	S	S								T	.	.	.	.	.	T	T									.	.	.	.	.	.	.	.	.	.				T	T
Template Predicted Secondary structure																																.	.	.	.	.											.	.	.	.	.	.	.	.	.	.
Template SS confidence
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.						.	.	.	.	.	.	.	430	.	.											.	.	.	.	.
		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.		.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																												.
Query SS confidence																																												.
Query Sequence		E	A	R	T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	.	K	K	N	E	D	L	S	V	D	K	K	T	E	M	I	L	Q
Query Conservation																																												.
Alig confidence																																												.
Template Conservation
Template Sequence		E	A	K	V	M	M	N	L	S	H	E	K	L	V	Q	L	Y	G	V	C	T	K	Q	R	P	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D
Template Known Secondary structure												T	T	B									S	S	S	S									T	T										G	G	G
Template Predicted Secondary structure
Template SS confidence
		445	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.		.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
Predicted Secondary structure																									.
Query SS confidence																									.
Query Sequence		A	A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	.	L	Y	T	D	G	K	V	K	I	S	D	F	G	L	T	R	N	G	T	V	Y	Q	I	K	P	N	T	K	S	P	I	R	W	L	A	I
Query Conservation																									.
Alig confidence																									.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	C	E	A	M	E	Y	L	E	S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K	V	S	D	F	G	F	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	R	W	S	P	P
Template Known Secondary structure												T	T				S			S	G	G	G					T	T												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G	G
Template Predicted Secondary structure																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		505	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.																.	.	.	.	.	.
		299	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	V	A	T	Q	V	A	N	G	Y	R	M	P	P	Y	P	H	A	Q	A	E	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	V	L	M	Y	S	K	F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	I	A	Q	G	L	R	L	Y	R	P	H	L	A	S	E	K	V
Template Known Secondary structure																											T	T	S			T	T	T	T	S											T	T							T	T	S
Template Predicted Secondary structure
Template SS confidence
		567	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.
		359	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I	L	Q	R	V	T	E	T	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	T	I	M	Y	S	C	W	H	E	K	A	D	E	R	P	T	F	K	I	L	L	S	N	I	L	D	V	M	D	E	E
Template Known Secondary structure								T	T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		627	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D