Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 59 Aligned Residues 264 % Identity 31% Template c3fupB_ PDB info PDB header:transferase Chain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 2.40 Å

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		121	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	F	W	E	L	E	H	D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L	A
Query Conservation
Alig confidence																																																		.	.
Template Conservation																																																		.	.
Template Sequence		D	P	T	Q	F	E	E	R	H	L	K	F	L	Q	Q	L	G	K	G	N	F	G	S	V	E	M	C	R	Y	D	P	L	Q	D	N	T	G	E	V	V	A	V	K	K	L	Q	H	S	.	.	T	E	E	H	L	R	D	F	E	R
Template Known Secondary structure			T	T				G	G	G											S	S										T	T	S	S	S											S			.	.
Template Predicted Secondary structure																																																		.	.
Template SS confidence
		840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.			.	.	890	.	.	.	.	.	.	.
		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.		.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																												.
Query SS confidence																																												.
Query Sequence		E	A	R	T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	.	K	K	N	E	D	L	S	V	D	K	K	T	E	M	I	L	Q
Query Conservation																																												.
Alig confidence																							.	.																				.
Template Conservation																							.	.
Template Sequence		E	I	E	I	L	K	S	L	Q	H	D	N	I	V	K	Y	K	G	V	C	Y	.	.	S	N	L	K	L	I	M	E	Y	L	P	Y	G	S	L	R	D	Y	L	Q	K	H	K	E	R	I	D	H	I	K	L	L	Q	Y	T	S	Q
Template Known Secondary structure								T				T	T	B									.	.											T	T		B					T	T	T	S	T	T	T
Template Predicted Secondary structure																							.	.
Template SS confidence
		898	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.			.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.		.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.			.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
Predicted Secondary structure																									.																	.	.
Query SS confidence																									.																	.	.
Query Sequence		A	A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	.	L	Y	T	D	G	K	V	K	I	S	D	F	G	L	T	R	.	.	N	G	T	V	Y	Q	I	K	P	N	T	K	S	P	I	R	W	L
Query Conservation																									.																	.	.
Alig confidence																									.																	.	.
Template Conservation
Template Sequence		I	C	K	G	M	E	Y	L	G	T	K	R	Y	I	H	R	D	L	A	T	R	N	I	L	V	E	N	E	N	R	V	K	I	G	D	F	G	L	T	K	V	L	P	Q	D	K	E	K	V	K	E	P	G	E	S	P	I	F	W	Y
Template Known Secondary structure											T	T	T								G	G	G						T	T								T	T						T	T							S	S				G	G	G
Template Predicted Secondary structure
Template SS confidence
		960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.																	.	.	.	.	.	.	.	340
Predicted Secondary structure																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		A	I	E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	M	K	P	A	D	V	A	T
Query Conservation																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																														.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																														.
Template Sequence		A	P	E	S	L	T	E	S	K	F	S	V	A	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	I	E	K	S	K	S	P	P	A	E	F	M	R	M	I	G	N	D	K	Q	G	Q	M	I	V	F	H	L	I	E
Template Known Secondary structure																														.	T	T		G	G	G	S											S				S	S
Template Predicted Secondary structure																														.
Template SS confidence
		1022	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.		1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080
		341	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	V	A	N	G	Y	R	M	P	P	Y	P	H	A	Q	A	E	I	Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I	L	Q	R	V	T	E	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	L	K	N	N	G	R	L	P	R	P	D	G	C	P	D	E	I	Y	M	I	M	T	E	C	W	N	N	N	V	N	Q	R	P	S	F	R	D	L	A	L	R	V	D	Q	I	R	D	Q
Template Known Secondary structure					T	T							T	T			T	T									T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1081	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D