|   |   |
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | T | I | H | K | K | L | G | E | G | A | F | G | E | V | S | S | G | V | M | K | F | K | K | G | M | K | T | V | Q | V | A | I | K | Q | V | K | L | D | K | T | G | K | A | K | I | K | D | F | L | A | E | A | R | T | M | R | K | L | G |
| Query Conservation |   |
  |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   | . | . | . | . |   |   |   |
|
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
| Template Sequence |   |
L | V | R | G | T | V | L | G | Q | E | D | P | Y | A | Y | L | E | A | T | . |
. |
. |
. |
D | Q | E | T | G | E | S | F | E | V | H | V | P | Y | F | T | E | R | A | I | K | Q | M | K | E | E | V | L | R | L | R | L | L | R | G | I | K |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  | . | . | . | . |  | T | T | T |
|
|  |  |  |  |  |  |  |
|
| S |
|
|
|
|  |  |  |  |  |  |  |  | G | G | G | G | S | T | T |
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
257 | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | |
|
|
|
. | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
|   |
|   |   |
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | 210 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
H | Q | N | I | I | K | F | Y | G | V | G | V | L | Q | E | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
L | Y | L | V | M | E | L | A | V | N | . |
. |
. |
. |
. |
. |
G | A | L | D | S | F | L | K | K | N | E | D | L | S | V | D | K | K | T |
| Query Conservation |   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |
|
|   |
|
|   |   |   | . | . | . | . | . | . |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
| Template Sequence |   |
N | Q | K | Q | A | K | V | H | L | R | F | I | F | P | F | D | L | V | K | D | P | Q | V | L | S | R | F | F | L | Y | P | R | M | Q | S | N | L | Q | T | F | G | E | V | L | L | S | H | S | S | T | H | K | S | L | V | H | H | A | R | L |
| Template Known Secondary structure |   |
S |  |  |  |  |  |  |  | T |
| B |
|
|
|
|  |  |  |  |
|
|
|
|
| S |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
317 | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . |
|   |
|   |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | |
|
|
|
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |
|
|
| . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
| Query Sequence |   |
E | M | I | L | Q | A | A | W | G | L | E | Y | I | H | G | K | P | M | L | H | R | D | I | A | A | R | N | C | . |
L | Y | T | D | G | K | V | K | I | S | D | F | G | L | T | R | N | G | T | V | Y | Q | I | K | P | N | T | . |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |
|   |   |   |
|
| . |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
| Template Conservation |   |
  |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Q | L | T | L | Q | V | I | R | L | L | A | S | L | H | H | Y | G | L | V | H | T | Y | L | R | P | V | D | I | V | L | D | Q | R | G | G | V | F | L | T | G | F | E | H | L | V | R | D | G | A | S | A | V | S | P | I | G | R | G | F | A |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
|
| G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
| G | G | G |
|  |  | T | T |  |  |  |
|
|
|
|
| T | T | T |
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
392 | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . |
|   |
|   |   |
|
|
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | |
. | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
. | . |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
K | S | P | I | R | W | L | A | I | E | T | I | K | T | M | I | . |
C | S | E | K | T | D | V | W | A | Y | G | V | L | C | W | E | I | F | N | N | A | A | E | P | Y | P | G | M | K | P | A | D | V | A | T | Q | V | A | N | G | Y |
| Query Conservation |   |
. | . |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   | . |   |   |   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
| Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
| Template Conservation |   |
  |
|
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|   |
|   |   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
| Template Sequence |   |
P | P | E | T | T | A | E | R | M | L | P | F | G | Q | H | H | P | T | L | M | T | F | A | F | D | T | W | T | L | G | L | A | I | Y | W | I | W | C | . |
A | D | L | P | N | T | D | D | A | A | L | G | G | S | E | W | I | . |
. |
. |
. |
| Template Known Secondary structure |   |
|  |  |  |  |  |  |  | T | S | T | T | G | G | G |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
|
|
|
| T | T | G | G | G | S |
| S | G | G | G | . | . | . | . |
| Template Predicted Secondary structure |   |
|
|  |  |
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
452 | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | |
490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | |
|
|
|
|   |
|   |   |
347 | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | M | P | P | Y | P | H | A | Q | A | E | I | Q | T | M | M | A | R | C | N | A | E | N | P | N | D | R | P | S | M | A | E | I | A | E |
| Query Conservation |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |
|
|   |   |
| Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |   |   |
|   |
| Template Sequence |   |
. |
F | R | S | C | K | N | I | P | Q | P | V | R | A | L | L | E | G | F | L | R | Y | P | K | E | D | R | L | L | P | L | Q | A | M | E |
| Template Known Secondary structure |   |
. | G | S | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
. |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
507 | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 |
|   |