Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 85 Aligned Residues 251 % Identity 29% Template c3d4qA_ PDB info PDB header:transferase Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase Resolution 2.80 Å

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		121	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	F	W	E	L	E	H	D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L	A
Query Conservation
Alig confidence																																.	.	.	.	.	.	.
Template Conservation																																.	.	.	.	.	.	.
Template Sequence		D	D	W	E	I	P	D	G	Q	I	T	V	G	Q	R	I	G	S	G	S	F	G	T	V	Y	K	G	K	W	H	.	.	.	.	.	.	.	G	D	V	A	V	K	M	L	N	V	T	A	P	T	P	Q	Q	L	Q	A	F	K	N
Template Known Secondary structure					B			T	T												T	T								S	S	.	.	.	.	.	.	.	S									S	S	S
Template Predicted Secondary structure																																.	.	.	.	.	.	.
Template SS confidence
		448	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.								.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500
		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.		.	.	230	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																	.
Query SS confidence																																																	.
Query Sequence		E	A	R	T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	K	K	N	E	D	.	L	S	V	D	K	K	T	E	M	I	L	Q
Query Conservation																																																	.
Alig confidence																				.																													.
Template Conservation																				.
Template Sequence		E	V	G	V	L	R	K	T	R	H	V	N	I	L	L	F	M	G	.	Y	S	T	K	P	Q	L	A	I	V	T	Q	W	C	E	G	S	S	L	Y	H	H	L	H	I	I	E	T	K	F	E	M	I	K	L	I	D	I	A	R	Q
Template Known Secondary structure							T	T				T	T	B						.				S	S	S									S	S		B							T	S
Template Predicted Secondary structure																				.
Template SS confidence
		501	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.		.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.		.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
Predicted Secondary structure																									.
Query SS confidence																									.
Query Sequence		A	A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	.	L	Y	T	D	G	K	V	K	I	S	D	F	G	L	T	R	N	G	T	V	Y	Q	I	K	P	N	T	K	S	P	I	R	W	L	A	I
Query Conservation																									.
Alig confidence																									.																					.	.	.	.	.	.	.	.	.
Template Conservation																																														.	.	.	.	.	.	.	.	.
Template Sequence		T	A	Q	G	M	D	Y	L	H	A	K	S	I	I	H	R	D	L	K	S	N	N	I	F	L	H	E	D	L	T	V	K	I	G	D	F	G	L	A	T	V	L	S	G	.	.	.	.	.	.	.	.	.	S	I	L	W	M	A	P
Template Known Secondary structure												T	T		B		S			S	G	G	G					T	T	T								T	T		B					.	.	.	.	.	.	.	.	.			T	T
Template Predicted Secondary structure																																														.	.	.	.	.	.	.	.	.
Template SS confidence
		560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.										.	.	.	.	.	.	610
		299	300	.	.	.	.	.				.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.		.	.	340	.	.	.	.	.	.	.	.	.					350
Predicted Secondary structure									.	.	.																																	.													.	.	.	.
Query SS confidence									.	.	.																																	.													.	.	.	.
Query Sequence		E	T	I	K	T	M	I	.	.	.	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	.	V	A	T	Q	V	A	N	G	Y	R	M	P	.	.	.	.	P
Query Conservation									.	.	.																																	.													.	.	.	.
Alig confidence									.	.	.																				.													.													.	.	.	.
Template Conservation																															.
Template Sequence		E	V	I	R	M	Q	D	K	N	P	Y	S	F	Q	S	D	V	Y	A	F	G	I	V	L	Y	E	L	M	T	.	G	Q	L	P	Y	S	N	I	N	N	R	D	Q	I	I	F	M	V	G	R	G	Y	L	S	P	D	L	S	K	V
Template Known Secondary structure					T	T		S	S				S																		.	S	S		T	T	T	T														T	S					G	G	G	S
Template Predicted Secondary structure																															.
Template SS confidence
		623	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.		.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.
		351	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	P	H	A	Q	A	E	I	Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I	L	Q	R	V	T	E	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	S	N	C	P	K	A	M	K	R	L	M	A	E	C	L	K	K	K	R	D	E	R	P	L	F	P	Q	I	L	A	S	I	E	L	L	A	R	S
Template Known Secondary structure			T	T	S												T		S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		682	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D