Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 222 Aligned Residues 251 % Identity 27% Template c3c1xA_ PDB info PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor Resolution 2.17 Å

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		121	.	.	.	.	.	.	.	.			130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.
Predicted Secondary structure											.	.
Query SS confidence											.	.
Query Sequence		Q	F	W	E	L	E	H	D	Q	.	.	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F
Query Conservation											.	.
Alig confidence											.	.																									.																.
Template Conservation																																					.																.
Template Sequence		Q	H	V	V	I	G	P	S	S	L	I	V	H	F	N	E	V	I	G	R	G	H	F	G	C	V	Y	H	G	T	L	L	D	N	D	.	G	K	K	I	H	C	A	V	K	S	L	N	R	I	T	.	D	I	G	E	V	S	Q	F
Template Known Secondary structure		T	T	T	B			S	T	T													S	S	S										T	T	.	T												S		S	.		S
Template Predicted Secondary structure																																					.																.
Template SS confidence
		1067	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.		.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.		.	.	.	1120	.	.	.	.
		179	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.			.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Predicted Secondary structure																																									.	.
Query SS confidence																																									.	.
Query Sequence		L	A	E	A	R	T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	.	.	L	D	S	F	L	K	K	N	E	D	L	S	V	D	K	K	T	E	M
Query Conservation																																									.	.
Alig confidence																																									.	.
Template Conservation
Template Sequence		L	T	E	G	I	I	M	K	D	F	S	H	P	N	V	L	S	L	L	G	I	C	L	R	S	E	G	S	P	L	V	V	L	P	Y	M	K	H	G	D	L	R	N	F	I	R	N	E	T	H	N	P	T	V	K	D	L	I	G	F
Template Known Secondary structure						T	T	S	T	T				T	T	B											S	S										T	T		B								T	T				B
Template Predicted Secondary structure
Template SS confidence
		1125	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.		270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.
Predicted Secondary structure																																			.
Query SS confidence																																			.
Query Sequence		I	L	Q	A	A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	L	Y	T	D	G	K	V	.	K	I	S	D	F	G	L	T	R	N	G	T	V	Y	Q	I	K	P	N	T	K	S	P	I	R	W
Query Conservation																																			.
Alig confidence																																			.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		G	L	Q	V	A	K	G	M	K	F	L	A	S	K	K	F	V	H	R	D	L	A	A	R	N	C	M	L	D	E	K	F	T	V	K	V	A	D	F	L	P	V	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	W
Template Known Secondary structure															T	T				S				G	G	G					T	T											G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G
Template Predicted Secondary structure																																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1185	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.																	.
		296	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	I	E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	V	A	T	Q	V	A	N	G	Y	R	M	P	P	Y	P	H	A	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	A	L	E	S	L	Q	T	Q	K	F	T	T	K	S	D	V	W	S	F	G	V	L	L	W	E	L	M	T	R	G	A	P	P	Y	P	D	V	N	T	F	D	I	T	V	Y	L	L	Q	G	R	R	L	L	Q	P	E	Y	C	P
Template Known Secondary structure		S																												T	T	S			S		T	T	S		S	S								T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.
		356	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	E	I	Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I	L	Q	R	V	T	E	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	P	L	Y	E	V	M	L	K	C	W	H	P	K	A	E	M	R	P	S	F	S	E	L	V	S	R	I	S	A	I	F	S	T
Template Known Secondary structure												T		S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D