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Job DescriptionQ22245
Confidence100.00%DateSun Jun 30 11:14:08 BST 2013
Rank159Aligned Residues259
% Identity33%Templatec2yhvA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of l1196m mutant anaplastic lymphoma kinase
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   121........130.........140.........150.........160.........170.........180
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Query Sequence  QFWELEHDQITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIKDFLA
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Template Sequence  DLKEVPRKNITL. . . IRGLAFGEVYEGQV. . . . . . . PLQVAVKTLP. EVCSEQDELDFLM
Template Known Secondary structure  GS
B

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   1107..1110........ .1120.........1130.. .......1140.. .......1150.....
 
   181........190.........200.........210.........220... ......230...
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Query Sequence  EARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVNGALDSFLK. . . . . . . KNEDLSVDKK
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Template Sequence  EALIISKFNHQNIVRCIGVSLQSLPRFILMELMAGGDLKSFLRETRPRPSQPSSLAMLDL
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   1167..1170.........1180.........1190.........1200.........1210.........1220......
 
   234.....240.........250.........260......... 270.........280.........290..
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Query Sequence  TEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDGKV. KISDFGLTRNGTVYQIKPNTKSP
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Template Sequence  LHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRGGCAMLP
Template Known Secondary structure  TT


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   1227..1230.........1240.........1250.........1260.........1270.........1280......
 
   293......300.........310.........320.........330.........340.........350..
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Query Sequence  IRWLAIETIKTMICSEKTDVWAYGVLCWEIFNNAAEPYPGMKPADVATQVANGYRMPPYP
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Template Sequence  VKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPK
Template Known Secondary structure  GGG





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   1293......1300.........1310.........1320.........1330.........1340.........1350..
 
   353......360.........370.........380.........390
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Query Sequence  HAQAEIQTMMARCNAENPNDRPSMAEIAEILQRVTETP
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Template Sequence  NCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDP
Template Known Secondary structure  T

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   1353......1360.........1370.........1380.........1390
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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