Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 314 Aligned Residues 244 % Identity 18% Template c2vx3D_ PDB info PDB header:transferase Chain: D: PDB Molecule:dual specificity tyrosine-phosphorylation- regulated PDBTitle: crystal structure of the human dual specificity tyrosine-2 phosphorylation-regulated kinase 1a Resolution 2.40 Å

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		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L	A	E	A	R	T	M	R	K
Query Conservation
Alig confidence																							.	.	.	.															.	.	.
Template Conservation																							.	.	.	.															.	.	.
Template Sequence		D	R	Y	E	I	D	S	L	I	G	K	G	S	F	G	Q	V	V	K	A	Y	.	.	.	.	D	R	V	E	Q	E	W	V	A	I	K	I	I	K	.	.	.	N	K	K	A	F	L	N	Q	A	Q	I	E	V	R	L	L	E	L
Template Known Secondary structure		T	T											T	T								.	.	.	.		T	T	T	T										.	.	.	S	S
Template Predicted Secondary structure																							.	.	.	.															.	.	.
Template SS confidence
		157	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.					.	.	180	.	.	.	.	.	.	.	.	.	190	.				.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
		188	.	190	.	.	.	.							.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.		.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Predicted Secondary structure									.	.	.	.	.	.																													.
Query SS confidence									.	.	.	.	.	.																													.
Query Sequence		L	G	H	Q	N	I	I	.	.	.	.	.	.	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	.	K	K	N	E	D	L	S	V	D	K	K	T	E	M	I	L	Q	A
Query Conservation									.	.	.	.	.	.																													.
Alig confidence									.	.	.	.	.	.																													.
Template Conservation
Template Sequence		M	N	K	H	D	T	E	M	K	Y	Y	I	V	H	L	K	R	H	F	M	F	R	N	H	L	C	L	V	F	E	M	L	S	Y	N	L	Y	D	L	L	R	N	T	N	F	R	G	V	S	L	N	L	T	R	K	F	A	Q	Q	M
Template Known Secondary structure					S	S	S	S	G	G	G	G	B										T	T												B								T	T	T
Template Predicted Secondary structure
Template SS confidence
		210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.						.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.
Predicted Secondary structure																								.	.	.	.	.
Query SS confidence																								.	.	.	.	.
Query Sequence		A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	.	.	.	.	.	L	Y	T	D	G	K	V	K	I	S	D	F	G	L	T	R	N	G	T	V	Y	Q	I	K	P	N	T	K	S	P	I	R	W
Query Conservation																								.	.	.	.	.
Alig confidence																								.	.	.	.	.																															.	.	.
Template Conservation																																																											.	.	.
Template Sequence		C	T	A	L	L	F	L	A	T	P	E	L	S	I	I	H	C	D	L	K	P	E	N	I	L	L	C	N	P	K	R	S	A	I	K	I	V	D	F	G	S	S	C	Q	L	G	Q	R	I	Y	Q	I	Q	S	R	F	Y	.	.	.
Template Known Secondary structure										S	T	T	T					S				G	G	G				S	S	T	T	S									T	T				T	T									G	G	G	.	.	.
Template Predicted Secondary structure																																																											.	.	.
Template SS confidence
		270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.
		296	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.
Predicted Secondary structure																																																			.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																			.	.	.	.	.	.	.	.	.	.	.
Query Sequence		L	A	I	E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	V	A	T	Q	V	A	N	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																			.	.	.	.	.	.	.	.	.	.	.
Alig confidence																															.																				.	.	.	.	.	.	.	.	.	.	.
Template Conservation																															.
Template Sequence		R	S	P	E	V	L	L	G	M	P	Y	D	L	A	I	D	M	W	S	L	G	C	I	L	V	E	M	H	T	.	G	E	P	L	F	S	G	A	N	E	V	D	Q	M	N	K	I	V	E	V	L	G	I	P	P	A	H	I	L	D
Template Known Secondary structure								T	T					T																	.	S	S		S	S			S	S														S							T
Template Predicted Secondary structure																															.
Template SS confidence
		328	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.		.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
																																																			345	.	.	.	.	350	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	Y	R	M	P	P	Y	P	H	A	Q
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		Q	A	P	K	A	R	K	F	F	E	K	L	P	D	G	T	W	N	L	K	K	T	K	R	E	Y	K	P	P	G	T	R	K	L	H	N	I	L	G	V	E	T	G	G	P	G	G	R	R	A	G	E	S	G	H	T	V	A	D	Y
Template Known Secondary structure		T		T	T	G	G	G	T					T	T	S											S			T	T		S						T	T	T	T	T	T	S	G	G	G	T	T	T	T		T	T
Template Predicted Secondary structure
Template SS confidence
		387	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
		356	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	E	I	Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	K	F	K	D	L	I	L	R	M	L	D	Y	D	P	K	T	R	I	Q	P	Y	Y	A	L	Q	H
Template Known Secondary structure												T		S		T	T	T	S								T	S
Template Predicted Secondary structure
Template SS confidence
		450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D