Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 306 Aligned Residues 251 % Identity 18% Template c2vagA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity protein kinase clk1; PDBTitle: crystal structure of di-phosphorylated human clk1 in2 complex with a novel substituted indole inhibitor Resolution 1.80 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		124	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	L	E	H	D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F	L	A	E	A	R
Query Conservation
Alig confidence																												.	.	.															.	.	.
Template Conservation																												.	.	.															.	.	.
Template Sequence		D	V	L	S	A	R	Y	E	I	V	D	T	L	G	E	G	A	F	G	K	V	V	E	C	I	D	.	.	.	H	K	A	G	G	R	H	V	A	V	K	I	V	K	.	.	.	N	V	D	R	Y	C	E	A	A	R	S	E	I	Q
Template Known Secondary structure					T	T	T											T	T									.	.	.	T	T	T	T	T										.	.	.	S	S
Template Predicted Secondary structure																												.	.	.															.	.	.
Template SS confidence
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180				.	.	.	.	.	.	.	.	.	190	.	.	.	.				.	.	.	.	.	200	.	.	.	.	.	.	.	.
		184	.	.	.	.	.	190	.	.	.							.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Predicted Secondary structure												.	.	.	.	.	.																									.
Query SS confidence												.	.	.	.	.	.																									.
Query Sequence		T	M	R	K	L	G	H	Q	N	I	.	.	.	.	.	.	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	.	L	D	S	F	L	K	K	N	E	D	L	S	V	D	K	K	T	E	M
Query Conservation												.	.	.	.	.	.																									.
Alig confidence												.	.	.	.	.	.																									.
Template Conservation
Template Sequence		V	L	E	H	L	N	T	T	D	P	N	S	T	F	R	C	V	Q	M	L	E	W	F	E	H	H	G	H	I	C	I	V	F	E	L	L	G	L	S	T	Y	D	F	I	K	E	N	G	F	L	P	F	R	L	D	H	I	R	K	M
Template Known Secondary structure											T	T		T	T		B										T	T												B								T	T	T
Template Predicted Secondary structure
Template SS confidence
		209	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.		.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.
Predicted Secondary structure																												.																																	.
Query SS confidence																												.																																	.
Query Sequence		I	L	Q	A	A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	.	L	Y	T	D	G	K	V	K	I	S	D	F	G	L	T	R	N	G	T	V	Y	Q	I	K	P	N	T	K	S	P	I	R	.
Query Conservation																												.																																	.
Alig confidence																												.																																	.
Template Conservation
Template Sequence		A	Y	Q	I	C	K	S	V	N	F	L	H	S	N	K	L	T	H	T	D	L	K	P	E	N	I	L	F	V	Q	S	D	Y	T	E	A	Y	N	K	R	D	E	R	T	L	I	N	P	D	I	K	V	V	D	F	G	S	A	T	Y
Template Known Secondary structure															T	T								G	G	G				S																	S										S	S
Template Predicted Secondary structure
Template SS confidence
		269	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.
													295	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	W	L	A	I	E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	V	A	T	Q	V	A
Query Conservation		.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.																															.
Template Conservation																																											.
Template Sequence		D	D	E	H	H	S	T	L	V	R	H	Y	R	A	P	E	V	I	L	A	L	G	W	S	Q	P	C	D	V	W	S	I	G	C	I	L	I	E	Y	Y	L	.	G	F	T	V	F	P	T	H	D	S	K	E	H	L	A	M	M	E
Template Known Secondary structure		T	T	S				S					S							T	T	S			S	T																	.	S	S		S				S
Template Predicted Secondary structure																																											.
Template SS confidence
		332	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.		.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390
		344																																												.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Predicted Secondary structure			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		N	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	Y	R	M	P	P	Y	P	H	A	Q	A	E	I	Q	T
Query Conservation			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		R	I	L	G	P	L	P	K	H	M	I	Q	K	T	R	K	R	K	Y	F	H	H	D	R	L	D	W	D	E	H	S	S	A	G	R	Y	V	S	R	A	C	K	P	L	K	E	F	M	L	S	Q	D	V	E	H	E	R	L	F	D
Template Known Secondary structure						S										S		G	G	G			T	T						T	T	S													G	G	G	G		S			S
Template Predicted Secondary structure
Template SS confidence
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.
		361	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	I	Q	K	M	L	E	Y	D	P	A	K	R	I	T	L	R	E	A	L	K
Template Known Secondary structure							T		S	S	T	T	T	S							T	T
Template Predicted Secondary structure
Template SS confidence
		453	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D