|   |   |
119 | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | R | Q | F | W | E | L | E | H | D | Q | I | T | I | H | K | K | L | G | E | G | A | F | G | E | V | S | S | G | V | M | K | F | K | K | G | M | K | T | V | Q | V | A | I | K | Q | V | K | L | D | K | T | G | K | A | K | I | K | D | F |
| Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   | . | . | . | . |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
P | S | S | N | P | H | A | K | P | S | D | F | H | F | L | K | V | I | G | K | G | S | F | G | K | V | L | L | A | R | . |
. |
. |
. |
H | K | A | E | E | V | F | Y | A | V | K | V | L | Q | K | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
T | T | B |
| T | T |
|
| G | G | G |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  |  | . | . | . | . |  | T | T | T |
|
|  |  |  |  |  |  |  |  | G | G | . | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |
|  |  | . | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
87 | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | |
|
|
|
|
|
|
|
|
|
|   |
|   |   |
179 | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | A | E | A | R | T | M | R | K | L | G | H | Q | N | I | I | K | F | Y | G | V | G | V | L | Q | E | P | L | Y | L | V | M | E | L | A | V | N | G | A | L | D | S | F | L | K | K | N | E | D | L | S | V | D | K | K | T | E | M | I | L |
| Query Conservation |   |
  |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
. |
A | I | L | V | L | L | K | N | V | K | H | P | F | L | V | G | L | H | F | S | F | Q | T | A | D | K | L | Y | F | V | L | D | Y | I | N | G | G | E | L | F | Y | H | L | Q | R | E | R | C | F | L | E | P | R | A | R | F | Y | A | A |
| Template Known Secondary structure |   |
. | G | B |
|
|
| B |
|
|
|
|
| T | T | B |
|
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |
|
|
| S |
| B |  |  |  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
. |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
133 | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . |
|   |
|   |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
. | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  | . |
|
|
|
|
|  |  |  |
|
|
|  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | A | A | W | G | L | E | Y | I | H | G | K | P | M | L | H | R | D | I | A | A | R | N | C | . |
L | Y | T | D | G | K | V | K | I | S | D | F | G | L | T | R | . |
N | G | T | V | Y | Q | I | K | P | N | T | K | S | P | I | R | W | L |
| Query Conservation |   |
  |
|   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |
|   |   |   |
|
| . |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | I | A | S | A | L | G | Y | L | H | S | L | N | I | V | Y | R | D | L | K | P | E | N | I | L | L | D | S | Q | G | H | I | V | L | T | D | F | G | L | C | K | E | N | I | E | H | N | S | T | T | S | T | F | C | G | T | P | E | Y | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
|
| B |
| G | G | G | B |
|
|
|
|
|
|
| S | B | S |
|
|
|
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
205 | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . |
|   |
|   |   |
297 | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | I | E | T | I | K | T | M | I | C | S | E | K | T | D | V | W | A | Y | G | V | L | C | W | E | I | F | N | N | A | A | E | P | Y | P | G | M | K | P | A | D | V | A | T | Q | V | A | N | G | Y | R | M | P | P | Y | P | H | A | Q | A |
| Query Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
A | P | E | V | L | H | K | Q | P | Y | D | R | T | V | D | W | W | C | L | G | A | V | L | Y | E | M | L | Y | . |
G | L | P | P | F | Y | S | R | N | T | A | E | M | Y | D | N | I | L | N | K | . |
P | L | Q | L | K | P | N | I | T | N |
| Template Known Secondary structure |   |
|  |  |  |  | T | T |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T |
|
| S | B |  |  |  |  |  |  |  |  |  |  | S | . |
|
|
|
|
| S | S | S |
|  |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
265 | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | |
. | . | . | . | . | . | . | 320 | . | . |
|   |
|   |   |
357 | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | I | Q | T | M | M | A | R | C | N | A | E | N | P | N | D | R | P | S | M | A | E | I | A | E | I | L |
| Query Conservation |   |
  |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |
|
|   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |
|
| Template Sequence |   |
S | A | R | H | L | L | E | G | L | L | Q | K | D | R | T | K | R | L | G | A | K | D | D | F | M | E | I |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S | T | T | T | T | T | T |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
323 | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
|   |