Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 5 Aligned Residues 377 % Identity 32% Template c2h8hA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor Resolution 2.20 Å Model Dimensions (Å) X:74.593 Y:61.259 Z:46.593

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		6	.	.	.			10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.					.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.
Predicted Secondary structure						.	.																												.	.	.	.
Query SS confidence						.	.																												.	.	.	.
Query Sequence		L	P	S	E	.	.	V	S	N	A	T	I	D	K	E	L	Y	Y	H	G	L	L	P	S	E	D	V	R	Q	L	L	S	N	.	.	.	.	N	G	D	F	L	L	R	S	S	E	P	E	P	G	S	P	R	T	H	I	L	S	V
Query Conservation						.	.																												.	.	.	.
Alig confidence						.	.																												.	.	.	.																.	.	.
Template Conservation																																																						.	.	.
Template Sequence		I	P	S	N	Y	V	A	P	S	D	S	I	Q	A	E	E	W	Y	F	G	K	I	T	R	R	E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	.	.	.	Y	C	L	S	V
Template Known Secondary structure				G	G	G				T	T	S	G	G	G	S	T	T	B			S											T		T	T			T	T								S	S	S	T	T		.	.	.
Template Predicted Secondary structure																																																						.	.	.
Template SS confidence
		132	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.				.	.	.	.	.
		60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.		.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.
Predicted Secondary structure																			.																																										.
Query SS confidence																			.																																										.
Query Sequence		M	F	N	N	R	L	D	D	I	N	S	I	K	H	F	V	V	.	N	F	V	D	G	K	Y	F	I	N	D	K	M	S	F	P	S	I	Q	K	M	L	G	T	Y	Q	R	N	N	T	E	I	K	E	G	C	M	L	V	N	P	.
Query Conservation																			.																																										.
Alig confidence												.							.																																										.
Template Conservation												.
Template Sequence		S	D	F	D	N	A	K	G	L	N	.	V	K	H	Y	K	I	R	K	L	D	S	G	G	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G	L	C	H	R	L	T	T	V	C	P	T
Template Known Secondary structure						T	T	T				.							B		.			S						T	T				S	S													T	T	S	S	S
Template Predicted Secondary structure												.
Template SS confidence
		189	190	.	.	.	.	.	.	.	.		.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.
									118	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170
Predicted Secondary structure		.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	I	R	R	Q	F	W	E	L	E	H	D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T
Query Conservation		.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.																																				.	.	.	.	.
Template Conservation																																												.	.	.	.	.
Template Sequence		S	K	P	Q	T	Q	G	L	A	K	D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T	.	.	.	.	.	T	R	V	A	I	K	T	L	K	P	G	T	M
Template Known Secondary structure							S	S	S	S	T	T		S	B			G	G	G											S	S									T	T	T	.	.	.	.	.										T	T	S	S
Template Predicted Secondary structure																																												.	.	.	.	.
Template SS confidence
		248	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.						290	.	.	.	.	.	.	.	.	.	300	.	.
		171	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.			.	.	.	.	.	.	.
Predicted Secondary structure																																																					.	.
Query SS confidence																																																					.	.
Query Sequence		G	K	A	K	I	K	D	F	L	A	E	A	R	T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	.	.	L	K	K	N	E	D	L
Query Conservation																																																					.	.
Alig confidence				.	.	.																											.																				.	.
Template Conservation				.	.	.																											.
Template Sequence		S	P	.	.	.	E	A	F	L	Q	E	A	Q	V	M	K	K	L	R	H	E	K	L	V	Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L
Template Known Secondary structure				.	.	.																T	T	B									.	S	S	S									T	T								S					T	T
Template Predicted Secondary structure				.	.	.																											.
Template SS confidence
		303	.				.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.
		229	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.		.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.			.	280	.	.	.	.	.
Predicted Secondary structure																																				.																	.	.
Query SS confidence																																				.																	.	.
Query Sequence		S	V	D	K	K	T	E	M	I	L	Q	A	A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	.	L	Y	T	D	G	K	V	K	I	S	D	F	G	L	T	R	.	.	N	G	T	V	Y	Q	I
Query Conservation																																				.																	.	.
Alig confidence																																				.																	.	.
Template Conservation
Template Sequence		R	L	P	Q	L	V	D	M	A	A	Q	I	A	S	G	M	A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A
Template Known Secondary structure																							T	T				S			S	G	G	G					G	G	G							T	T	S	T	T	T								T
Template Predicted Secondary structure
Template SS confidence
		359	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.
		286	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	P	N	T	K	S	P	I	R	W	L	A	I	E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	V	A	T	Q	V	A	N	G
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G
Template Known Secondary structure		T		S	T	T	S		G	G	G	S																											T	T	T	T			S	S	T	T												T	T
Template Predicted Secondary structure
Template SS confidence
		419	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.
		346	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	R	M	P	P	Y	P	H	A	Q	A	E	I	Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I	L	Q	R	V	T	E	T	P	R	P	N	F	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	L	M	C	Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y	F	T	S	T	E	P	Q	Q	P
Template Known Secondary structure								T	T													T		S	S	G	G	G	S												T	S	S				S
Template Predicted Secondary structure
Template SS confidence
		479	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D