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Job DescriptionQ22245
Confidence100.00%DateSun Jun 30 11:14:08 BST 2013
Rank6Aligned Residues357
% Identity32%Templatec2c0iA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
Resolution2.30 Å
Model Dimensions (Å)X:60.490 Y:74.543 Z:47.811

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   13......20.........30...... ...40.........50.........60........
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Query Sequence  ATIDKELYYHGLLPSEDVRQLLSN. . . . NGDFLLRSSEPEPGSPRTHILSVMFNNRLDDI
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Template Sequence  DSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGS. . . YSLSVRDYDPRQGD
Template Known Secondary structure  TSGGGSTTTT

TSTT

TT

SSSTT
...TTT
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   116...120.........130.........140.........150........ .160.........170..
 
   6970...... ...80.........90.........100.........110... ......120
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Query Sequence  NSIKHFVV. NFVDGKYFINDKMSFPSIQKMLGTYQRNNTEIKEGCM. . . . . . . LVNPIRR
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Template Sequence  T. VKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEK
Template Known Secondary structure  .B

STT
SSTTSSSTTSS
SS
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T
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   173 ......180.........190.........200.........210.........220.........230.
 
   121........130.........140.........150.........160.........170.........180
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Query Sequence  QFWELEHDQITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIKDFLA
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Template Sequence  DAWEIPRESLKLEKKLGAGQFGEVWMATYN. . . . . KHTKVAVKTMKPGSMSVEA. . . FLA
Template Known Secondary structure  T
SB

GGGTTT.....TT


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   232.......240.........250.........260. ........270.........280 ...
 
   181........190.........200.........210.........220....... ..230........
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Query Sequence  EARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVNGALDSFLKKNED. . LSVDKKTEMIL
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Template Sequence  EANVMKTLQHDKLVKLHAVV. TKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSA
Template Known Secondary structure  T


TTB

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BSTTGGG

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   284.....290.........300... ......310.........320.........330.........340..
 
   239240.........250.........260.. .......270.........280.........290.......
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Query Sequence  QAAWGLEYIHGKPMLHRDIAARNC. LYTDGKVKISDFGLTRNGTVYQIKPNTKSPIRWLA
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Template Sequence  QIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVI. . . . . . . . . . . PIKWTA
Template Known Secondary structure  TT


S

SGGG
TT



TTGGGT
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   343......350.........360.........370.........380..... ....390.
 
   298.300.........310.........320.........330.........340.........350.......
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Query Sequence  IETIKTMICSEKTDVWAYGVLCWEIFNNAAEPYPGMKPADVATQVANGYRMPPYPHAQAE
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Template Sequence  PEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEE
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TTT

SSTT

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   405....410.........420.........430.........440.........450.........460....
 
   358.360.........370.........380.........390...
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Query Sequence  IQTMMARCNAENPNDRPSMAEIAEILQRVTETPRPN
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Template Sequence  LYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ
Template Known Secondary structure  T
SSGGGS

TTTS
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   465....470.........480.........490.........500
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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