|   |   |
117 | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | I | R | R | Q | F | W | E | L | E | H | D | Q | I | T | I | H | K | K | L | G | E | G | A | F | G | E | V | S | S | G | V | M | K | F | K | K | G | M | K | T | V | Q | V | A | I | K | Q | V | K | L | D | K | T | G | K | A | K | I | K |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   | . | . | . |   |   |   |   |   |   |   |
|
|
|
|   |
| . | . | . | . | . |   |   |   |   |   |   |
| Template Sequence |   |
P | Y | D | A | S | K | W | E | F | P | R | D | R | L | K | L | G | K | P | L | G | R | Q | V | I | E | A | D | A | F | G | I | D | . |
. |
. |
K | T | A | T | C | R | T | V | A | V | K | M | L | . |
. |
. |
. |
. |
T | H | S | E | H | R |
| Template Known Secondary structure |   |
|
|
|  |  |  |  | B |
|
| G | G | G |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  | S | T | T | . | . | . | S | S | S |
|  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . |
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
819 | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | |
|
|
. | . | . | . | . | . | . | . | 860 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 870 |
|   |
|   |   |
177 | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | |
. | . | . | . | . | . | . | . | . | 200 | . | . | |
. | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | |
|
|
|
|
|
|
. | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
| Query Sequence |   |
D | F | L | A | E | A | R | T | M | R | K | L | G | H | . |
Q | N | I | I | K | F | Y | G | V | G | V | L | . |
Q | E | P | L | Y | L | V | M | E | L | A | V | N | G | A | L | D | S | F | L | K | K | . |
. |
. |
. |
. |
. |
. |
N | E | D |
| Query Conservation |   |
  |
|   |   |
|   |   |   |
|   |   |
|   |
| . |
|
|
|
|   |   |   |
|   |   |   |   | . |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
| Template Conservation |   |
  |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
A | L | M | S | E | L | K | I | L | I | H | I | G | H | H | L | N | V | V | N | L | L | G | A | C | T | K | P | G | G | P | L | M | V | I | V | E | F | C | K | F | G | N | L | S | T | Y | L | R | S | K | R | N | E | F | V | P | Y | D | F |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |
| S | S | S | S |
|
|  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |  | T | T | T | S | B |
|
|
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
879 | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . |
|   |
|   |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | S | V | D | K | K | T | E | M | I | L | Q | A | A | W | G | L | E | Y | I | H | G | K | P | M | L | H | R | D | I | A | A | R | N | C | . |
L | Y | T | D | G | K | V | K | I | S | D | F | G | L | T | R | N | G | T | V | Y | Q | I | K |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |
|   |   |   |
|
| . |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
L | T | L | E | H | L | I | C | Y | S | F | Q | V | A | K | G | M | E | F | L | A | S | R | K | C | I | H | R | D | L | A | A | R | N | I | L | L | S | E | K | N | V | V | K | I | C | D | F | P | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |
|
|
| G | G | G |  |  |  |
| G | G | G |
|  |  |  |
|
|
|
| G | . | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
998 | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|   |
|   |   |
287 | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | |
. | . | . | . | . | . | 340 | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | N | T | K | S | P | I | R | W | L | A | I | E | T | I | K | T | M | I | C | S | E | K | T | D | V | W | A | Y | G | V | L | C | W | E | I | F | N | N | A | A | E | P | Y | P | G | M | . |
K | P | A | D | V | A | T | Q | V | A | N | G |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |   | . |   |   |   |   |
|   |   |   |
|   |   |
|
| Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
K | W | M | A | P | E | T | I | F | D | R | V | Y | T | I | Q | S | D | V | W | S | F | G | V | L | L | W | E | I | F | S | L | G | A | S | P | Y | P | G | V | K | I | D | E | E | F | C | R | R | L | K | E | G |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | G | G |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| S | S | T | T |
|
|
| S |  |  |  |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
1068 | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 |
|   |
|   |   |
346 | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | R | M | P | P | Y | P | H | A | Q | A | E | I | Q | T | M | M | A | R | C | N | A | E | N | P | N | D | R | P | S | M | A | E | I | A | E | I | L | Q | R | V | T | E | T |
| Query Conservation |   |
  |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
|
|   |   |
|
|
|   |
| Template Sequence |   |
T | R | M | R | A | P | D | Y | T | T | P | E | M | Y | Q | T | M | L | D | C | W | H | G | E | P | S | Q | R | P | T | F | S | E | L | V | E | H | L | G | N | L | L | Q | A |
| Template Known Secondary structure |   |
|
|
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1121 | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . |
|   |