Job Description Q22245 Confidence 100.00% Date Sun Jun 30 11:14:08 BST 2013 Rank 2 Aligned Residues 361 % Identity 33% Template c1oplA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase Resolution 3.42 Å Model Dimensions (Å) X:77.312 Y:64.084 Z:48.592

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		13	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.			.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Predicted Secondary structure																										.	.
Query SS confidence																										.	.
Query Sequence		A	T	I	D	K	E	L	Y	Y	H	G	L	L	P	S	E	D	V	R	Q	L	L	S	N	.	.	N	G	D	F	L	L	R	S	S	E	P	E	P	G	S	P	R	T	H	I	L	S	V	M	F	N	N	R	L	D	D	I	N	S
Query Conservation																										.	.
Alig confidence																										.	.																.	.	.											.	.	.	.	.	.
Template Conservation																																											.	.	.											.	.	.	.	.	.
Template Sequence		N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	.	.	.	R	S	I	S	L	R	Y	E	G	R	.	.	.	.	.	.
Template Known Secondary structure		S	S	G	G	G	S	T	T														G	G	G			T	T								S	S	S	T	T		.	.	.								T	T		.	.	.	.	.	.
Template Predicted Secondary structure																																											.	.	.											.	.	.	.	.	.
Template SS confidence
		139	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.				180	.	.	.	.	.	.	.	.	.
		71	.	.	.	.	.		.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Predicted Secondary structure								.																																													.	.	.	.	.	.	.	.	.
Query SS confidence								.																																													.	.	.	.	.	.	.	.	.
Query Sequence		I	K	H	F	V	V	.	N	F	V	D	G	K	Y	F	I	N	D	K	M	S	F	P	S	I	Q	K	M	L	G	T	Y	Q	R	N	N	T	E	I	K	E	G	C	M	L	V	N	P	I	R	R	.	.	.	.	.	.	.	.	.
Query Conservation								.																																													.	.	.	.	.	.	.	.	.
Alig confidence								.																																													.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P
Template Known Secondary structure											T	T	S				S	S	T	T	S		B	S	S									T	T			T	T	S	S	S										S					S	S	S		S
Template Predicted Secondary structure
Template SS confidence
		190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.
				121	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.
Query SS confidence		.	.
Query Sequence		.	.	Q	F	W	E	L	E	H	D	Q	I	T	I	H	K	K	L	G	E	G	A	F	G	E	V	S	S	G	V	M	K	F	K	K	G	M	K	T	V	Q	V	A	I	K	Q	V	K	L	D	K	T	G	K	A	K	I	K	D	F
Query Conservation		.	.
Alig confidence		.	.																																		.	.	.	.																		.	.	.
Template Conservation																																					.	.	.	.																		.	.	.
Template Sequence		N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	.	.	.	.	L	T	V	A	V	K	T	L	K	E	D	T	M	E	V	E	E	.	.	.	F
Template Known Secondary structure		S	S	S			B			G	G	G							S	G	G	G	T	T	S	S							G	G	G	T	.	.	.	.										S	S	S	S					.	.	.
Template Predicted Secondary structure																																					.	.	.	.																		.	.	.
Template SS confidence
		250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.					.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.				.
		179	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.			.	.	.	.	.	.	230	.	.	.	.	.	.
Predicted Secondary structure																																															.	.
Query SS confidence																																															.	.
Query Sequence		L	A	E	A	R	T	M	R	K	L	G	H	Q	N	I	I	K	F	Y	G	V	G	V	L	Q	E	P	L	Y	L	V	M	E	L	A	V	N	G	A	L	D	S	F	L	K	.	.	K	N	E	D	L	S	V	D	K	K	T	E	M
Query Conservation																																															.	.
Alig confidence																																															.	.
Template Conservation
Template Sequence		L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A	V	V	L	L	Y	M
Template Known Secondary structure														T	T	B									S	S	S	S									T	T		B								S		T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		303	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.		.	.	270	.	.	.	.	.	.	.	.			.	280	.	.	.	.	.	.	.	.	.	290	.	.	.
Predicted Secondary structure																																	.												.	.
Query SS confidence																																	.												.	.
Query Sequence		I	L	Q	A	A	W	G	L	E	Y	I	H	G	K	P	M	L	H	R	D	I	A	A	R	N	C	L	Y	T	D	G	.	K	V	K	I	S	D	F	G	L	T	R	.	.	N	G	T	V	Y	Q	I	K	P	N	T	K	S	P	I
Query Conservation																																	.												.	.
Alig confidence																																	.												.	.
Template Conservation
Template Sequence		A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I
Template Known Secondary structure															T	T				S			S	G	G	G					G	G	G							T	T						T	T							T	T					G
Template Predicted Secondary structure
Template SS confidence
		363	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.
		294	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	W	L	A	I	E	T	I	K	T	M	I	C	S	E	K	T	D	V	W	A	Y	G	V	L	C	W	E	I	F	N	N	A	A	E	P	Y	P	G	M	K	P	A	D	V	A	T	Q	V	A	N	G	Y	R	M	P	P	Y	P	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K	D	Y	R	M	E	R	P	E	G
Template Known Secondary structure		G	G																													T	T	S			S	S	T	T			T	T	T							T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		423	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.
		354	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	Q	A	E	I	Q	T	M	M	A	R	C	N	A	E	N	P	N	D	R	P	S	M	A	E	I	A	E	I	L	Q	R	V	T	E	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q	E
Template Known Secondary structure														T		S	S	G	G	G	S												T	S		S	S
Template Predicted Secondary structure
Template SS confidence
		483	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D