Job Description O01798 Confidence 100.00% Date Fri May 3 21:22:31 BST 2013 Rank 7 Aligned Residues 359 % Identity 29% Template c4fl2A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch Resolution 2.19 Å Model Dimensions (Å) X:85.631 Y:50.648 Z:85.126

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		110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.					130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.
Predicted Secondary structure																						.	.	.	.
Query SS confidence																						.	.	.	.
Query Sequence		D	N	F	P	F	Y	H	G	F	M	G	R	N	E	C	E	A	M	L	S	.	.	.	.	N	H	G	D	F	L	I	R	M	T	E	I	G	K	R	V	A	Y	V	I	S	I	K	W	K	Y	Q	N	I	H	V	L	V	K	R	T	K	T	K	K	L	Y	W	T	K	K	Y	A	F	K	S	I	C	E	L	I
Query Conservation																						.	.	.	.
Alig confidence																						.	.	.	.												.	.
Template Conservation																																					.	.
Template Sequence		E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	.	.	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V
Template Known Secondary structure		G	G	S	T	T	B			S												S	S	S			T	T									.	.	T	T	T									T	T											T	T	S				S	T	T				B	S	S
Template Predicted Secondary structure																																					.	.
Template SS confidence
		164	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.			.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
		186	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.																											210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		A	Y	H	K	R	N	H	K	P	I	Y	E	G	M	T	L	I	C	G	L	A	R	H	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	W	Q	L	N	N	E	Q	V	T	L	N	K	K	L	G	E	G	Q	F	G	E	V	H	K	G	S	L	K	T	S
Query Conservation																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	T	Q	R	E	A	L	P	M	D	T	E	V	Y	E	S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K
Template Known Secondary structure					T	T	B		T	T	S	S	S				S	B				S				T	T			G	G	G	S	G	G	G	S		G	G	G	S	T	T	S				S	S	S	B			G	G	G												T	T											T
Template Predicted Secondary structure
Template SS confidence
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	F	A	A	P	V	T	V	A	V	K	T	L	H	Q	N	H	L	S	A	N	E	K	I	L	F	L	R	E	A	N	V	M	L	T	L	S	H	P	N	V	I	K	F	Y	G	V	C	T	M	K	E	P	I	M	I	V	M	E	F	C	D	G	K	S	L	E	D	A	L	L	S	K	E	E	K	V	S	A	E
Query Conservation
Alig confidence		.	.																																															.																								.
Template Conservation		.	.																																															.																								.
Template Sequence		.	.	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	.	N	R	H	V	K	D	K
Template Known Secondary structure		.	.	T												S	G	G	G		G	G	G																	T	T	B								.		S	S	S									T	T		B								.		T	T	S
Template Predicted Secondary structure		.	.																																															.																								.
Template SS confidence
				394	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.		.	.	.	.	.	.	.
		320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.					.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.
Predicted Secondary structure																																																							.	.	.	.
Query SS confidence																																																							.	.	.	.
Query Sequence		D	K	I	L	Y	L	F	H	A	A	C	G	I	D	Y	L	H	G	K	Q	V	I	H	R	D	I	A	A	R	N	C	L	L	N	S	K	K	I	L	K	I	S	D	F	G	L	S	V	K	G	V	A	I	.	.	.	.	K	E	R	K	G	G	C	L	P	V	K	Y	M	A	P	E	T	L	K	K	G	L	Y
Query Conservation																																																							.	.	.	.
Alig confidence																																																							.	.	.	.
Template Conservation
Template Sequence		N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F
Template Known Secondary structure																				T	T				S			S	G	G	G						T	T							T	T					T	T								S		B	T	T	B		G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.
		396	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	T	A	S	D	I	Y	S	Y	G	A	L	M	Y	E	V	Y	T	D	G	K	T	P	F	E	T	C	G	L	R	G	N	E	L	R	K	A	I	I	G	K	R	I	S	L	A	V	E	V	E	L	P	V	F	I	A	N	I	F	E	Q	S	R	Q	Y	E	T	E	D	R	I	S	S	K	Q	I	I	Q	I	F
Query Conservation
Alig confidence																										.	.																.
Template Conservation																										.	.																.
Template Sequence		S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	.	.	R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	.	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L
Template Known Secondary structure																			T	T	T			S	S	.	.	T	T												T	T	.							T	T													T		S	S	T	T	T	S
Template Predicted Secondary structure																										.	.																.
Template SS confidence
		550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.			.	.	.	.	.	.	580	.	.	.	.	.	.	.	.		.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.
		476	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	N
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		627	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D