Job Description O01798 Confidence 100.00% Date Fri May 3 21:22:31 BST 2013 Rank 87 Aligned Residues 242 % Identity 26% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		209	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	W	Q	L	N	N	E	Q	V	T	L	N	K	K	L	G	E	G	Q	F	G	E	V	H	K	G	S	L	K	T	S	V	F	A	A	P	V	T	V	A	V	K	T	L	H	Q	N	H	L	S	A	N	E	K	I	L	F	L	R	E	A	N	V	M	L	T	L	S	H	P	N	V	I	K	F	Y	G	V	C	T
Query Conservation
Alig confidence																																	.	.	.	.													.	.	.	.	.	.	.	.
Template Conservation																																	.	.	.	.													.	.	.	.	.	.	.	.
Template Sequence		E	Y	D	Y	E	Y	D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	D	L	S	N	.	.	.	.	Q	V	R	I	A	I	K	E	I	P	E	Q	.	.	.	.	.	.	.	.	P	L	H	E	E	I	A	L	H	K	H	L	K	H	K	N	I	V	Q	Y	L	G	S	F	S
Template Known Secondary structure							B		T	T	S	S	B							S	S	S								T	T	T	.	.	.	.													.	.	.	.	.	.	.	.										T	T				T	T	B
Template Predicted Secondary structure																																	.	.	.	.													.	.	.	.	.	.	.	.
Template SS confidence
		672	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.					.	.	.	.	.	.	.	710	.	.	.	.									.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.
		289	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.			.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.		.	.	.	.	.	.	.	360	.	.	.	.	.
Predicted Secondary structure																														.	.																																					.
Query SS confidence																														.	.																																					.
Query Sequence		M	K	E	P	I	M	I	V	M	E	F	C	D	G	K	S	L	E	D	A	L	L	S	K	E	E	K	V	.	.	S	A	E	D	K	I	L	Y	L	F	H	A	A	C	G	I	D	Y	L	H	G	K	Q	V	I	H	R	D	I	A	A	R	N	C	L	L	.	N	S	K	K	I	L	K	I	S	D	F	G	L
Query Conservation																														.	.																																					.
Alig confidence																														.	.																																					.
Template Conservation
Template Sequence		E	N	G	F	I	K	I	F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K	Y	L	H	D	N	Q	I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G	T
Template Known Secondary structure			T	T										T	T		B								T	T				T	T																						T	T				S			S	G	G	G					T	T	T									S	S
Template Predicted Secondary structure
Template SS confidence
		746	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.
		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.			.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.
Predicted Secondary structure																															.	.
Query SS confidence																															.	.
Query Sequence		S	V	K	G	V	A	I	K	E	R	K	G	G	C	L	P	V	K	Y	M	A	P	E	T	L	K	K	G	L	.	.	Y	S	T	A	S	D	I	Y	S	Y	G	A	L	M	Y	E	V	Y	T	D	G	K	T	P	F	E	T	C	G	L	R	G	N	E	L	R	K	A	I	I	G	K	R	I	S	L	A	V	E
Query Conservation																															.	.
Alig confidence							.	.	.	.	.	.	.	.	.																.	.																				.							.
Template Conservation							.	.	.	.	.	.	.	.	.																																					.							.
Template Sequence		S	K	R	L	T	.	.	.	.	.	.	.	.	.	G	T	L	Q	Y	M	A	P	E	I	I	D	K	G	P	R	G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	.	G	K	P	P	F	Y	.	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H	P	E	I	P
Template Known Secondary structure							.	.	.	.	.	.	.	.	.			G	G	G										G	G	G		S																		.	S	S		T	T	G	.	G	G		S												T
Template Predicted Secondary structure							.	.	.	.	.	.	.	.	.																																					.							.
Template SS confidence
		826	.	.	.	830										.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.		.	.	.	870	.	.		.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.
		444	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	E	L	P	V	F	I	A	N	I	F	E	Q	S	R	Q	Y	E	T	E	D	R	I	S	S	K	Q	I	I	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	S	M	S	A	E	A	K	A	F	I	L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	L	V
Template Known Secondary structure		T	T	S												T		S		T	T	T	S								T
Template Predicted Secondary structure
Template SS confidence
		905	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D