Job Description O01798 Confidence 100.00% Date Fri May 3 21:22:31 BST 2013 Rank 125 Aligned Residues 254 % Identity 29% Template c3v5qB_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models Resolution 2.20 Å

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		210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.		.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.
Predicted Secondary structure																					.
Query SS confidence																					.
Query Sequence		W	Q	L	N	N	E	Q	V	T	L	N	K	K	L	G	E	G	Q	F	.	G	E	V	H	K	G	S	L	K	T	S	V	F	A	A	P	V	T	V	A	V	K	T	L	H	Q	N	H	L	S	A	N	E	K	I	L	F	L	R	E	A	N	V	M	L	T	L	S	H	P	N	V	I	K	F	Y	G	V	C	T
Query Conservation																					.
Alig confidence																					.												.	.	.	.													.	.
Template Conservation																																	.	.	.	.													.	.
Template Sequence		Q	H	I	K	R	R	D	I	V	L	K	R	E	L	G	F	K	V	F	L	A	E	C	Y	N	L	S	P	T	K	D	.	.	.	.	K	M	L	V	A	V	K	A	L	K	D	P	.	.	T	L	A	A	R	K	D	F	Q	R	E	A	E	L	L	T	N	L	Q	H	E	H	I	V	K	F	Y	G	V	C	G
Template Known Secondary structure						G	G	G																		S			S	S	S	S	.	.	.	.											S		.	.																					T	T	B
Template Predicted Secondary structure																																	.	.	.	.													.	.
Template SS confidence
		531	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.					.	.	.	.	.	.	.	.	570	.	.	.			.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.
		289	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	K	E	P	I	M	I	V	M	E	F	C	D	G	K	S	L	E	D	A	L	L	S	K	E	E	K	V	S	A	E	D	K	I	L	Y	L	F	H	A	A	C	G	I	D	Y	L	H	G	K	Q	V	I	H	R	D	I	A	A	R	N	C	L	L	N	S	K	K	I	L	K	I	S	D	F	G	L	S	V	K
Query Conservation
Alig confidence				.	.																																																																											.	.
Template Conservation				.	.																																																																											.	.
Template Sequence		D	P	.	.	L	I	M	V	F	E	Y	M	K	H	G	D	L	N	K	F	L	R	A	H	G	P	E	L	G	L	S	Q	M	L	H	I	A	S	Q	I	A	S	G	M	V	Y	L	A	S	Q	H	F	V	H	R	D	L	A	T	R	N	C	L	V	G	A	N	L	L	V	K	I	G	D	F	G	M	D	.	.
Template Known Secondary structure				.	.									T	T									T	T																										T	T				S			S	G	G	G					G	G	G											.	.
Template Predicted Secondary structure				.	.																																																																											.	.
Template SS confidence
		609	610			.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.
		369	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	V	A	I	K	E	R	K	G	G	C	L	P	V	K	Y	M	A	P	E	T	L	K	K	G	L	Y	S	T	A	S	D	I	Y	S	Y	G	A	L	M	Y	E	V	Y	T	D	G	K	T	P	F	E	T	C	G	L	R	G	N	E	L	R	K	A	I	I	G	K	R	I	S	L	A	V	E	V	E	L	P	V
Query Conservation
Alig confidence		.																																																			.	.																		.
Template Conservation		.																																																			.	.																		.
Template Sequence		.	V	Y	S	T	D	Y	Y	R	T	M	L	P	I	R	W	M	P	P	E	S	I	M	Y	R	K	F	T	T	E	S	D	V	W	S	F	G	V	I	L	W	E	I	F	T	Y	G	K	Q	P	W	.	.	F	Q	L	S	N	T	E	V	I	E	C	I	T	Q	G	R	V	.	L	E	R	P	R	V	C	P	K
Template Known Secondary structure		.		S	G	G	G		B				B		G	G	G																												T	T	T	S			T	T	.	.	T	T	S												T			.					T	T
Template Predicted Secondary structure		.																																																			.	.																		.
Template SS confidence
			704	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.			.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770		.	.	.	.	.	.	.	.	.
		449	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	I	A	N	I	F	E	Q	S	R	Q	Y	E	T	E	D	R	I	S	S	K	Q	I	I	Q	I	F	K	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	V	Y	D	V	M	L	G	C	W	Q	R	E	P	Q	Q	R	L	N	I	K	E	I	Y	K	I	L	H	A
Template Known Secondary structure													S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		798	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D